Infants with perinatal hypoxic ischemia : feasibility of fiber tracking at birth and 3 months

C. Pul, van, J. Buijs, A. Vilanova, F.G. Roos, P.F.F. Wijn

Research output: Contribution to journalArticleAcademicpeer-review

19 Citations (Scopus)

Abstract

The purpose of our study was to retrospectively investigate the feasibility of using fibertracking to detect disturbances in white matter development in newborns suffering fromhypoxic-ischemia, at birth and at the age of 3 months. Diffusion Tensor Images wereobtained from full-term newborns, 7 with normal MRI and 10 with pathology related toperinatal hypoxic-ischemia. All parents gave informed consent. Visualization of whitematter tracts was investigated using a volume tracing and quantification technique.Fiber tracking was useful to study the neonatal brain. Pathology resulted in differentfiber patterns, compared to normal. Frequently affected were the corona radiata fibers.
Original languageEnglish
Pages (from-to)203-214
JournalRadiology
Volume240
Issue number1
DOIs
Publication statusPublished - 2006

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