In vitro and in vivo datasets of topically applied ketorolac tromethamine in aqueous humor using Raman spectroscopy

Shuo Zhang, Christian J.F. Bertens (Corresponding author), Roel J. Erckens, Frank J.H.M. van den Biggelaar, Tos T.J.M. Berendschot, Carroll A.B. Webers, Rudy M.M.A. Nuijts, Marlies Gijs

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Abstract

This article includes datasets acquired by Raman spectroscopy from in vivo and in vitro ocular samples collected from the dataset from Bertens and Zhang et al., “Confocal Raman spectroscopy: Evaluation of a non-invasive technique for the detection of topically applied ketorolac tromethamine in vitro and in vivo” (Bertens and Zhang, et al.). Detection of ketorolac tromethamine in pig eyes was performed in vitro and rabbit eyes in vivo. Extracted aqueous humor samples from pig and rabbit eyes were measured in vitro using a cuvette. This manuscript shows the spectral Raman data without pre-treatment or analysis from ocular tissues and provides further information towards aqueous humor research via alternative data processing methods. Furthermore, the raw data enclosed may be used for future aqueous humor investigations and pharmaceutical research.

Original languageEnglish
Article number104694
Number of pages9
JournalData in Brief
Volume27
DOIs
Publication statusPublished - Dec 2019

Keywords

  • Raman spectroscopy
  • Ophthalmology
  • Ketorolac tromethamine
  • Rabbits
  • Aqueous humor
  • Pig eyes

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