In silico identification of an interferon inhibitor

M. Kaiser; C. Ottmann

doi:10.1002/cmdc.201100579

In silico identification of an interferon inhibitor

M. Kaiser, C. Ottmann

Chemical Biology

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Inhibition of IFNa–IFNR: Interferon (IFN) is an important signaling molecule and antiviral therapeutic agent. However, in certain diseases like type I diabetes, IFN action can be harmful. Schneider and co-workers recently reported the identification of the first IFNa–IFNR inhibitor via in silico screening, which binds to IFNa and impedes interferon signaling in cells.

Original language	English
Pages (from-to)	555-557
Number of pages	3
Journal	ChemMedChem : chemistry enabling drug discovery
Volume	7
Issue number	4
DOIs	https://doi.org/10.1002/cmdc.201100579
Publication status	Published - 2012

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