Impact of postoperative renal replacement therapy on long-term outcome after cardiac surgery increases with age

Marco C. Haanschoten; Albert H.M. van Straten; Arthur Bouwman; Alexander J.G.H. Bindels; André A.J. van Zundert; Mohamed A. Soliman Hamad

doi:10.1111/jocs.12335

Impact of postoperative renal replacement therapy on long-term outcome after cardiac surgery increases with age

Marco C. Haanschoten, Albert H.M. van Straten, Arthur Bouwman, Alexander J.G.H. Bindels, André A.J. van Zundert, Mohamed A. Soliman Hamad

Research output: Contribution to journal › Article › Academic › peer-review

5 Citations (Scopus)

Abstract

BACKGROUND AND AIM OF THE STUDY: In the present study, we investigated the survival of patients who received postoperative renal replacement therapy (RRT) after cardiac surgery. We specifically focused on factors predicting long-term outcome in elderly patients.

METHODS: Data of all patients that received unintentional renal replacement therapy following cardiac surgery between 2004 and 2010 were analyzed. Logistic- and Cox regression analyses were performed to detect the predictors of early and late mortality, respectively.

RESULTS: During the study period, 11,899 patients underwent cardiac surgery in our center. Post-operative RRT was performed in 138 patients (1.2%). In this group of patients, 30-day mortality included 72 patients (52%) and the total overall mortality included 107 patients (77.5%). Regression analyses revealed that age predicted 30-day mortality (odds ratio = 1.08 [1.03 to 1.12]) as well as late mortality (odds ratio = 1.05 [1.02 to 1.07].

CONCLUSIONS: Patients requiring RRT after cardiac surgery have a poor prognosis with a high mortality. Older age predicted both 30-day and late mortality in these patients.

Original language	English
Pages (from-to)	464-469
Number of pages	6
Journal	Journal of Cardiac Surgery
Volume	29
Issue number	4
DOIs	https://doi.org/10.1111/jocs.12335
Publication status	Published - Jul 2014

Keywords

Acute Kidney Injury/therapy
Age Factors
Aged
Cardiac Surgical Procedures
Female
Humans
Logistic Models
Male
Postoperative Care
Postoperative Complications/therapy
Proportional Hazards Models
Renal Replacement Therapy/mortality
Risk Factors
Survival Rate
Time Factors
Treatment Outcome

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10.1111/jocs.12335

Cardiovascular Medicine
van de Laar, L. (Content manager) & Jansen, J. (Content manager)
Impact: Research Topic/Theme (at group level)

Cite this

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title = "Impact of postoperative renal replacement therapy on long-term outcome after cardiac surgery increases with age",

abstract = "BACKGROUND AND AIM OF THE STUDY: In the present study, we investigated the survival of patients who received postoperative renal replacement therapy (RRT) after cardiac surgery. We specifically focused on factors predicting long-term outcome in elderly patients.METHODS: Data of all patients that received unintentional renal replacement therapy following cardiac surgery between 2004 and 2010 were analyzed. Logistic- and Cox regression analyses were performed to detect the predictors of early and late mortality, respectively.RESULTS: During the study period, 11,899 patients underwent cardiac surgery in our center. Post-operative RRT was performed in 138 patients (1.2%). In this group of patients, 30-day mortality included 72 patients (52%) and the total overall mortality included 107 patients (77.5%). Regression analyses revealed that age predicted 30-day mortality (odds ratio = 1.08 [1.03 to 1.12]) as well as late mortality (odds ratio = 1.05 [1.02 to 1.07].CONCLUSIONS: Patients requiring RRT after cardiac surgery have a poor prognosis with a high mortality. Older age predicted both 30-day and late mortality in these patients.",

keywords = "Acute Kidney Injury/therapy, Age Factors, Aged, Cardiac Surgical Procedures, Female, Humans, Logistic Models, Male, Postoperative Care, Postoperative Complications/therapy, Proportional Hazards Models, Renal Replacement Therapy/mortality, Risk Factors, Survival Rate, Time Factors, Treatment Outcome",

author = "Haanschoten, {Marco C.} and {van Straten}, {Albert H.M.} and Arthur Bouwman and Bindels, {Alexander J.G.H.} and {van Zundert}, {Andr{\'e} A.J.} and {Soliman Hamad}, {Mohamed A.}",

note = "{\textcopyright} 2014 Wiley Periodicals, Inc.",

year = "2014",

month = jul,

doi = "10.1111/jocs.12335",

language = "English",

volume = "29",

pages = "464--469",

journal = "Journal of Cardiac Surgery",

issn = "0886-0440",

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TY - JOUR

T1 - Impact of postoperative renal replacement therapy on long-term outcome after cardiac surgery increases with age

AU - Haanschoten, Marco C.

AU - van Straten, Albert H.M.

AU - Bouwman, Arthur

AU - Bindels, Alexander J.G.H.

AU - van Zundert, André A.J.

AU - Soliman Hamad, Mohamed A.

PY - 2014/7

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N2 - BACKGROUND AND AIM OF THE STUDY: In the present study, we investigated the survival of patients who received postoperative renal replacement therapy (RRT) after cardiac surgery. We specifically focused on factors predicting long-term outcome in elderly patients.METHODS: Data of all patients that received unintentional renal replacement therapy following cardiac surgery between 2004 and 2010 were analyzed. Logistic- and Cox regression analyses were performed to detect the predictors of early and late mortality, respectively.RESULTS: During the study period, 11,899 patients underwent cardiac surgery in our center. Post-operative RRT was performed in 138 patients (1.2%). In this group of patients, 30-day mortality included 72 patients (52%) and the total overall mortality included 107 patients (77.5%). Regression analyses revealed that age predicted 30-day mortality (odds ratio = 1.08 [1.03 to 1.12]) as well as late mortality (odds ratio = 1.05 [1.02 to 1.07].CONCLUSIONS: Patients requiring RRT after cardiac surgery have a poor prognosis with a high mortality. Older age predicted both 30-day and late mortality in these patients.

AB - BACKGROUND AND AIM OF THE STUDY: In the present study, we investigated the survival of patients who received postoperative renal replacement therapy (RRT) after cardiac surgery. We specifically focused on factors predicting long-term outcome in elderly patients.METHODS: Data of all patients that received unintentional renal replacement therapy following cardiac surgery between 2004 and 2010 were analyzed. Logistic- and Cox regression analyses were performed to detect the predictors of early and late mortality, respectively.RESULTS: During the study period, 11,899 patients underwent cardiac surgery in our center. Post-operative RRT was performed in 138 patients (1.2%). In this group of patients, 30-day mortality included 72 patients (52%) and the total overall mortality included 107 patients (77.5%). Regression analyses revealed that age predicted 30-day mortality (odds ratio = 1.08 [1.03 to 1.12]) as well as late mortality (odds ratio = 1.05 [1.02 to 1.07].CONCLUSIONS: Patients requiring RRT after cardiac surgery have a poor prognosis with a high mortality. Older age predicted both 30-day and late mortality in these patients.

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KW - Age Factors

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KW - Cardiac Surgical Procedures

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KW - Humans

KW - Logistic Models

KW - Male

KW - Postoperative Care

KW - Postoperative Complications/therapy

KW - Proportional Hazards Models

KW - Renal Replacement Therapy/mortality

KW - Risk Factors

KW - Survival Rate

KW - Time Factors

KW - Treatment Outcome

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DO - 10.1111/jocs.12335

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SN - 0886-0440

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EP - 469

JO - Journal of Cardiac Surgery

JF - Journal of Cardiac Surgery

IS - 4

ER -

Impact of postoperative renal replacement therapy on long-term outcome after cardiac surgery increases with age

Abstract

Keywords

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Cardiovascular Medicine

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