Impact of Additives on Mechanical Properties of Supramolecular Electrospun Scaffolds

Bastiaan D Ippel, Eline E Van Haaften, Carlijn V C Bouten, Patricia Y W Dankers (Corresponding author)

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

Abstract

The mechanical properties of scaffolds used for mechanically challenging applications such as cardiovascular implants are unequivocally important. Here, the effect of supramolecular additive functionalization on mechanical behavior of electrospun scaffolds was investigated for one bisurea-based model additive and two previously developed antifouling additives. The model additive has no effect on the mechanical properties of the bulk material, whereas the stiffness of electrospun scaffolds was slightly decreased compared to pristine PCL-BU following the addition of the three different additives. These results show the robustness of supramolecular additives used in biomedical applications, in which mechanical properties are important, such as vascular grafts and heart valve constructs.

Original languageEnglish
Pages (from-to)3742-3748
Number of pages7
JournalACS Applied Polymer Materials
Volume2
Issue number9
DOIs
Publication statusPublished - 11 Sept 2020

Bibliographical note

Copyright © 2020 American Chemical Society.

Funding

This work was funded by the European Research Council (FP7/2007–2013) ERC Grant Agreement No. 308045, the Ministry of Education, Culture and Science (Gravity Program 024.001.035), and ZonMW as part of the LSH 2Treat program (Project No. 436001003).

FundersFunder number
Seventh Framework Programme
European Research Council308045
ZonMw : Dutch Organisation for Health Research and Development436001003
Ministerie van Onderwijs, Cultuur en Wetenschap024.001.035

    Keywords

    • additives
    • biomaterials
    • electrospinning
    • mechanics
    • multiscale
    • supramolecular chemistry

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