Hysteroscopic morcellation versus loop resection for removal of placental remnants: a randomized trial

Tjalina W.O. Hamerlynck, Huib A.A.M. van Vliet, Anne Sophie Beerens, Steven Weyers, Benedictus C. Schoot

Research output: Contribution to journalArticleAcademicpeer-review

10 Citations (Scopus)

Abstract

Study Objective:To compare hysteroscopic morcellation with loop resection for the removal of placental remnants in terms of procedure time, adverse events, tissue availability, histology results, short-term effectiveness, and postoperative adhesions. Design A randomized controlled trial (Canadian Task Force classification I). Setting A teaching and university hospital. Patients Women with placental remnants. Interventions Hysteroscopic morcellation with the TRUCLEAR 8.0 Tissue Removal System (Smith & Nephew, Inc, Andover, MA) or loop resection with a rigid 8.5-mm bipolar resectoscope (Karl Storz GmbH, Tuttlingen, Germany). Measurements and Main Results Forty-six and 40 women were included in the hysteroscopic morcellation and resection groups, respectively. The median operating time was significantly shorter for hysteroscopic morcellation compared with loop resection (6.2 minutes [interquartile range, 4.0–11.2 minutes] vs 10.0 minutes [5.8–16.4 minutes], p = .023). Both operating time and total procedure time, corrected for the diameter of the placental remnants, were significantly reduced for hysteroscopic morcellation compared with loop resection, by 40% (95% confidence interval, 15%–58%; p = .005) and 22% (95% CI, 5%–37%; p = .014), respectively. No adverse events occurred during hysteroscopic removal. Perforation at dilation in 8 cases of the hysteroscopic morcellation group resulted in 2 procedure discontinuations and 1 incomplete procedure. Incomplete removal was found in 1 uncomplicated hysteroscopic morcellation procedure and 2 resection procedures. Pathology results confirmed the presence of placental remnants in 27 of 40 (67.5%) and 26 of 37 (70%) patients in the hysteroscopic morcellation and resection groups, respectively. Second-look hysteroscopy showed de novo intrauterine adhesions in 1 of 35 patients (3%) in the hysteroscopic morcellation group and 1 of 30 (3%) patients in the resection group. Conclusion Hysteroscopic morcellation is a faster alternative than loop resection. Both techniques are safe and show high rates of complete removal and tissue availability and low rates of de novo intrauterine adhesions.

Original languageEnglish
Pages (from-to)1172-1180
Number of pages9
JournalJournal of Minimally Invasive Gynecology
Volume23
Issue number7
DOIs
Publication statusPublished - 1 Nov 2016
Externally publishedYes

Keywords

  • Hysteroscopic morcellation
  • Intrauterine adhesions
  • Loop resection
  • Placental remnants
  • Randomized controlled trial

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