TY - JOUR
T1 - Hypoxia affects mesenchymal stromal cell osteogenic differentiation and angiogenic factor expression
AU - Potier, E.
AU - Ferreira, E.
AU - Andriamanalijaona, R.
AU - Pujol, J.P.
AU - Oudina, K.
AU - Logeart-Avramoglou, D.
AU - Petite, H.
PY - 2007
Y1 - 2007
N2 - Mesenchymal stromal cells (MSCs) seeded onto biocompatible scaffolds have been proposed for repairing bone defects. When transplanted in vivo, MSCs (expanded in vitro in 21% O(2)) undergo temporary oxygen deprivation due to the lack of pre-existing blood vessels within these scaffolds. In the present study, the effects of temporary (48 h) exposure to hypoxia (
AB - Mesenchymal stromal cells (MSCs) seeded onto biocompatible scaffolds have been proposed for repairing bone defects. When transplanted in vivo, MSCs (expanded in vitro in 21% O(2)) undergo temporary oxygen deprivation due to the lack of pre-existing blood vessels within these scaffolds. In the present study, the effects of temporary (48 h) exposure to hypoxia (
U2 - 10.1016/j.bone.2006.11.024
DO - 10.1016/j.bone.2006.11.024
M3 - Article
SN - 8756-3282
VL - 40
SP - 1078
EP - 1087
JO - Bone
JF - Bone
IS - 4
ER -