Abstract
Confining treatment to the tumor to improve therapeutic outcome and reduce toxicity, is a hot issue in cancer research. Hyperthermia is recognized as a strong sensitizer for radiotherapy and chemotherapy enhancing tumor control without increasing toxicity. Today's electromagnetic hyperthermia systems heat large tissue volumes with limited ability to selectively heat the tumor. Fortunately, tremendous improvements in 3-dimensional electromagnetic & temperature modelling provide an exciting opportunity to design advanced multi-element electromagnetic applicator systems. Together with feedback control using MR non-invasive thermometry and smart E-field sensors, this paves the way for selective tumor heating and potentially prescription of a thermal dose. A technological advanced hyperthermia system, with guaranteed delivery of high quality hyperthermia lowers the threshold for newcomers to apply hyperthermia. Combined with recent proof that hyperthermia blocks DNA repair and new, exciting, ways for controlled drug delivery using temperature sensitive liposome encapsulated drugs, this is expected to increase interest of the medical community in hyperthermia.
Original language | English |
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Title of host publication | 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) : 16-20 Aug. 2016. |
Place of Publication | Piscataway |
Publisher | Institute of Electrical and Electronics Engineers |
Pages | 359-362 |
Number of pages | 4 |
ISBN (Electronic) | 978-1-4577-0220-4 |
ISBN (Print) | 978-1-4577-0219-8 |
DOIs | |
Publication status | Published - Aug 2016 |
Externally published | Yes |
Event | 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016 - Disney’s Contemporary Resort , Orlando, United States Duration: 16 Aug 2016 → 20 Aug 2016 Conference number: 38 http://embc.embs.org/2016/ |
Conference
Conference | 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016 |
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Abbreviated title | EMBC 2016 |
Country/Territory | United States |
City | Orlando |
Period | 16/08/16 → 20/08/16 |
Internet address |
Keywords
- Clinical Trials as Topic
- Electromagnetic Fields
- Humans
- Hyperthermia, Induced/methods
- Microwaves
- Neoplasms/therapy
- Temperature