Hydrolases part I : enzyme mechanism, selectivity and control in the synthesis of well-defined polymers

M.A.J. Veld, A.R.A. Palmans

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

16 Citations (Scopus)
4 Downloads (Pure)

Abstract

Lipases are highly activity in the polymerization of a range of monomers. Both ring-opening polymerization of cyclic esters and polycondensation reactions of AA–BB and AB monomers have been investigated in great detail. This paper reviews the increased understanding in enzymatic strategies for the production of well-defined polymers. Major advantages of enzymatic catalysts are the relatively mild reaction conditions, and the often-observed excellent regio-, chemo-, and enantioselectivity that allow for the direct preparation of functional materials. However, as a result of the monomer activation mechanism, polymers of low polydispersity and low quantitative degree of endgroup functionality are difficult to attain. A wide variety of (co)polymers have been synthesized and explored in a variety of applications using lipase catalysts.
Original languageEnglish
Title of host publicationEnzymatic polymerisation
EditorsA.R.A. Palmans, A. Heise
Place of PublicationBerlin
PublisherSpringer
Pages55-78
Number of pages159
ISBN (Print)978-3-642-16375-3
DOIs
Publication statusPublished - 2010

Publication series

NameAdvances in polymer science
Volume237
ISSN (Print)0065-3195

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