Highly sustainable catalytic dehydrogenation of alcohols with evolution of hydrogen gas

G.B.W.L. Ligthart, R.H. Meijer, M.P.J. Donners, J. Meuldijk, J.A.J.M. Vekemans, L.A. Hulshof

Research output: Contribution to journalArticleAcademicpeer-review

85 Citations (Scopus)

Abstract

The catalytic dehydrogenation of alcs. into aldehydes and ketones in the absence of H-acceptors was studied with several transition metal catalysts in order to develop a large-scale procedure. Applying Ru(OCOCF3)2(CO)(PPh3)2, the so called Robinson catalyst, several secondary alcs. could be dehydrogenated with high selectivity into the corresponding ketones in relatively short reaction times. Highly effective atom utilization could be realized avoiding solvents and giving hydrogen gas as the sole byproduct. However, in contrast to Robinson's work the catalytic dehydrogenation of primary alcs. appeared to be problematic due to decarbonylation with concomitant catalyst deactivation and aldol condensation under the strong acid or basic conditions applied. [on SciFinder (R)]
Original languageEnglish
Pages (from-to)1507-1509
JournalTetrahedron Letters
Volume44
Issue number7
DOIs
Publication statusPublished - 2003

Fingerprint Dive into the research topics of 'Highly sustainable catalytic dehydrogenation of alcohols with evolution of hydrogen gas'. Together they form a unique fingerprint.

  • Cite this