TY - GEN
T1 - Highlighting the nuances behind interaction of picosecond pulses with human skin
T2 - Optical Interactions with Tissue and Cells XXIX 2018
AU - Uzunbajakava, Natallia E.
AU - Varghese, Babu
AU - Botchkareva, Natalia V.
AU - Verhagen, Rieko
AU - Vogel, Alfred
PY - 2018
Y1 - 2018
N2 - In recent years, several commercial systems relying on picosecond pulses have been introduced into the field of cutaneous interventions. In parallel with this development, a somewhat distinct research prototype also operating in the picosecond regime was described in literature. Albeit both market-available products and the investigational device employ laser beams of nearly the same pulse duration and were reported to cause laser-induced optical breakdown (LIOB), they are different in terms of wavelength, applied fluence, laser beam quality, optical architecture and related focusing optics, resulting in different histomorphological features (such as e.g. lesion size, location, expression of collagen). Understanding the differences between these systems in relation to implications for clinical results raises a need in highlighting the nuances behind interaction of picosecond pulses with biological tissue. To achieve this, we accentuate the interplay of irradiance levels of picosecond pulses in W/cm2, absorption properties of a target tissue at a wavelength of a light source and resulting interaction mechanisms with biological object. We also relate these nuances to potential consequences for cutaneous interventions.
AB - In recent years, several commercial systems relying on picosecond pulses have been introduced into the field of cutaneous interventions. In parallel with this development, a somewhat distinct research prototype also operating in the picosecond regime was described in literature. Albeit both market-available products and the investigational device employ laser beams of nearly the same pulse duration and were reported to cause laser-induced optical breakdown (LIOB), they are different in terms of wavelength, applied fluence, laser beam quality, optical architecture and related focusing optics, resulting in different histomorphological features (such as e.g. lesion size, location, expression of collagen). Understanding the differences between these systems in relation to implications for clinical results raises a need in highlighting the nuances behind interaction of picosecond pulses with biological tissue. To achieve this, we accentuate the interplay of irradiance levels of picosecond pulses in W/cm2, absorption properties of a target tissue at a wavelength of a light source and resulting interaction mechanisms with biological object. We also relate these nuances to potential consequences for cutaneous interventions.
KW - Laser-induced optical breakdown (LIOB)
KW - laser-tissue interaction
KW - multiphoton ionization-induced LIOB (MI-LIOB)
KW - photo-thermo-mechanical disruption (PTMD)
KW - photodisruption
KW - picosecond laser device
KW - plasma-induced ablation
KW - thermionic emission-induced LIOB (TILIOB)
UR - http://www.scopus.com/inward/record.url?scp=85047332713&partnerID=8YFLogxK
U2 - 10.1117/12.2307804
DO - 10.1117/12.2307804
M3 - Conference contribution
AN - SCOPUS:85047332713
SN - 9781510614697
T3 - Proceedings of SPIE
BT - Optical Interactions with Tissue and Cells XXIX
A2 - Jansen, E. Duco
A2 - Beier, Hope Thomas
PB - SPIE
Y2 - 29 January 2018 through 30 January 2018
ER -