Heat transfer in patients under hypothermic conditions

F.E.M. Janssen, G.M.J. Leeuwen, van, A.A. Steenhoven, van

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Abstract

Most bio-heat transfer models for patients under hypothermic conditions contain three sub-models: a passive heat transfer model, an active coupling between local blood flow and temperature, and a pharmacological model to incorporate the effects of drugs. In this paper an illustrative example will be given focussed on scalp cooling to prevent chemotherapy induced hair loss. Scalp cooling can reduce hair loss. Unfortunately, the efficacy of scalp cooling varies strongly. A systematic evaluation of the current hypothesis for the hair preservative effect of scalp cooling is necessary for a better understanding of the various important parameters of scalp cooling. To quantify the contribution of the putative mechanisms of scalp cooling, a computational model was developed, partly based on experimental data. With the complete model, we evaluated the effect of several scalp cooling protocol parameters.
Original languageEnglish
Title of host publicationProceedings of the 7th World Conference on Experimental Heat Transfer, Fluid Mechanics and Thermodynamics (ExHFT-7), Krakow, Poland, 28th June-3rd July 2009
Place of PublicationPoland, Krakow
Pages71-80
Publication statusPublished - 2009
Eventconference; ExHFT-7: 7th World Conference on Experimental Heat Transfer, Fluid Mechanics and Thermodynamics; 2009-06-28; 2009-07-03 -
Duration: 28 Jun 20093 Jul 2009

Conference

Conferenceconference; ExHFT-7: 7th World Conference on Experimental Heat Transfer, Fluid Mechanics and Thermodynamics; 2009-06-28; 2009-07-03
Period28/06/093/07/09
OtherExHFT-7: 7th World Conference on Experimental Heat Transfer, Fluid Mechanics and Thermodynamics

Fingerprint

Heat transfer
Cooling
Chemotherapy
Blood

Cite this

Janssen, F. E. M., Leeuwen, van, G. M. J., & Steenhoven, van, A. A. (2009). Heat transfer in patients under hypothermic conditions. In Proceedings of the 7th World Conference on Experimental Heat Transfer, Fluid Mechanics and Thermodynamics (ExHFT-7), Krakow, Poland, 28th June-3rd July 2009 (pp. 71-80). Poland, Krakow.
Janssen, F.E.M. ; Leeuwen, van, G.M.J. ; Steenhoven, van, A.A. / Heat transfer in patients under hypothermic conditions. Proceedings of the 7th World Conference on Experimental Heat Transfer, Fluid Mechanics and Thermodynamics (ExHFT-7), Krakow, Poland, 28th June-3rd July 2009. Poland, Krakow, 2009. pp. 71-80
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title = "Heat transfer in patients under hypothermic conditions",
abstract = "Most bio-heat transfer models for patients under hypothermic conditions contain three sub-models: a passive heat transfer model, an active coupling between local blood flow and temperature, and a pharmacological model to incorporate the effects of drugs. In this paper an illustrative example will be given focussed on scalp cooling to prevent chemotherapy induced hair loss. Scalp cooling can reduce hair loss. Unfortunately, the efficacy of scalp cooling varies strongly. A systematic evaluation of the current hypothesis for the hair preservative effect of scalp cooling is necessary for a better understanding of the various important parameters of scalp cooling. To quantify the contribution of the putative mechanisms of scalp cooling, a computational model was developed, partly based on experimental data. With the complete model, we evaluated the effect of several scalp cooling protocol parameters.",
author = "F.E.M. Janssen and {Leeuwen, van}, G.M.J. and {Steenhoven, van}, A.A.",
year = "2009",
language = "English",
pages = "71--80",
booktitle = "Proceedings of the 7th World Conference on Experimental Heat Transfer, Fluid Mechanics and Thermodynamics (ExHFT-7), Krakow, Poland, 28th June-3rd July 2009",

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Janssen, FEM, Leeuwen, van, GMJ & Steenhoven, van, AA 2009, Heat transfer in patients under hypothermic conditions. in Proceedings of the 7th World Conference on Experimental Heat Transfer, Fluid Mechanics and Thermodynamics (ExHFT-7), Krakow, Poland, 28th June-3rd July 2009. Poland, Krakow, pp. 71-80, conference; ExHFT-7: 7th World Conference on Experimental Heat Transfer, Fluid Mechanics and Thermodynamics; 2009-06-28; 2009-07-03, 28/06/09.

Heat transfer in patients under hypothermic conditions. / Janssen, F.E.M.; Leeuwen, van, G.M.J.; Steenhoven, van, A.A.

Proceedings of the 7th World Conference on Experimental Heat Transfer, Fluid Mechanics and Thermodynamics (ExHFT-7), Krakow, Poland, 28th June-3rd July 2009. Poland, Krakow, 2009. p. 71-80.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

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AU - Steenhoven, van, A.A.

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N2 - Most bio-heat transfer models for patients under hypothermic conditions contain three sub-models: a passive heat transfer model, an active coupling between local blood flow and temperature, and a pharmacological model to incorporate the effects of drugs. In this paper an illustrative example will be given focussed on scalp cooling to prevent chemotherapy induced hair loss. Scalp cooling can reduce hair loss. Unfortunately, the efficacy of scalp cooling varies strongly. A systematic evaluation of the current hypothesis for the hair preservative effect of scalp cooling is necessary for a better understanding of the various important parameters of scalp cooling. To quantify the contribution of the putative mechanisms of scalp cooling, a computational model was developed, partly based on experimental data. With the complete model, we evaluated the effect of several scalp cooling protocol parameters.

AB - Most bio-heat transfer models for patients under hypothermic conditions contain three sub-models: a passive heat transfer model, an active coupling between local blood flow and temperature, and a pharmacological model to incorporate the effects of drugs. In this paper an illustrative example will be given focussed on scalp cooling to prevent chemotherapy induced hair loss. Scalp cooling can reduce hair loss. Unfortunately, the efficacy of scalp cooling varies strongly. A systematic evaluation of the current hypothesis for the hair preservative effect of scalp cooling is necessary for a better understanding of the various important parameters of scalp cooling. To quantify the contribution of the putative mechanisms of scalp cooling, a computational model was developed, partly based on experimental data. With the complete model, we evaluated the effect of several scalp cooling protocol parameters.

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Janssen FEM, Leeuwen, van GMJ, Steenhoven, van AA. Heat transfer in patients under hypothermic conditions. In Proceedings of the 7th World Conference on Experimental Heat Transfer, Fluid Mechanics and Thermodynamics (ExHFT-7), Krakow, Poland, 28th June-3rd July 2009. Poland, Krakow. 2009. p. 71-80