Fuzzy modeling for Vitamin B12 deficiency

A.M. Wilbik, S.L.M. van Loon, A.K. Boer, U. Kaymak, V. Scharnhorst

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

3 Citations (Scopus)
6 Downloads (Pure)

Abstract

Blood vitamin B12 levels are not representative for actual vitamin B12 status in tissue. Instead plasma methylmalonic acid (MMA) levels can be measured because MMA concentrations increase relatively early in the course of vitamin B12 deficiency. However, MMA levels in plasma may also be increased due to renal failure. In this paper we estimate the influence of the kidney function on MMA levels in plasma by using fuzzy inference systems. Using this method diagnosing vitamin B12 deficiencies could be improved when kidney failure is present.

Original languageEnglish
Title of host publication16th International Conference on Information Processing and Management of Uncertainty in Knowledge-Based Systems (IPMU 2016), June 20-24, 2016, Eindhoven, The Netherlands
EditorsJ. Carvalho, M.J. Lesot , U. Kaymak, S. Vieira, B. Bouchon-Meunier, R. Yager
Place of PublicationBerlin
PublisherSpringer
Pages462-471
Number of pages10
ISBN (Print)9783319405957
DOIs
Publication statusPublished - 2016
Event16th International Conference on Information Processing and Management of Uncertainty in Knowledge-Based Systems (IPMU 2016) - Eindhoven University of Technology , Eindhoven, Netherlands
Duration: 20 Jun 201624 Jun 2016
Conference number: 16
http://is.ieis.tue.nl/ipmu/

Publication series

NameCommunications in Computer and Information Science
Volume610
ISSN (Print)18650929

Conference

Conference16th International Conference on Information Processing and Management of Uncertainty in Knowledge-Based Systems (IPMU 2016)
Abbreviated titleIPMU 2016
Country/TerritoryNetherlands
CityEindhoven
Period20/06/1624/06/16
Internet address

Keywords

  • Kidney function
  • Takagi-Sugono fuzzy inference system
  • Vitamin B12 deficiency

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