Fractional flow reserve in unstable angina and non-ST-segment elevation myocardial infarction experience from the FAME (Fractional flow reserve versus Angiography for Multivessel Evaluation) study

J.W.E.M. Sels, W.A.L. (Pim) Tonino, U. Siebert, W.F. Fearon, M. Veer, van 't, B. Bruyne, de, N.H.J. Pijls

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125 Citations (Scopus)
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Abstract

The use of fractional flow reserve (FFR) to guide percutaneous coronary intervention (PCI) is well established in stable angina (SA) but has not been prospectively researched in unstable angina (UA) or non–ST-segment elevation myocardial infarction (NSTEMI). The FAME (Fractional flow reserve versus Angiography for Multivessel Evaluation) study compared angiography-guided PCI with FFR-guided PCI in patients with multivessel disease and included patients with SA and UA or NSTEMI. At 2 years, the benefit of using FFR to guide PCI does not differ between patients with UA or NSTEMI, compared with patients with SA.
Original languageEnglish
Pages (from-to)1183-1189
Number of pages7
JournalJACC: Cardiovascular Interventions
Volume4
Issue number11
DOIs
Publication statusPublished - 2011

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