Abstract
Pressing a rubber stamp inked with carboxylic acids onto an amine-terminated surface leads to the formation of amide bonds at room temperature (see scheme). Oligopeptides were created on the surface in this way from a monolayer. This rapid and uncatalyzed formation of amide bonds is attributed to the nanoscale confinement of the molecules between the stamp and the preorganized monolayer substrate. PDMS=poly(dimethylsiloxane).
Original language | English |
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Pages (from-to) | 4190-4193 |
Number of pages | 4 |
Journal | Angewandte Chemie - International Edition |
Volume | 43 |
Issue number | 32 |
DOIs | |
Publication status | Published - 2004 |