Fluorescent π-conjugated polymer dots versus self-assembled small molecule nanoparticles : what’s the difference?

I. Fischer, A.G. Kaeser, M.A.M. Peters-Gumbs, A.P.H.J. Schenning

Research output: Contribution to journalArticleAcademicpeer-review

20 Citations (Scopus)

Abstract

Fluorescent nanoparticles based on p-conjugated small molecules and polymers are two different classes of p-conjugated systems that have attracted much interest. To date, both emerging classes have only been studied separately and showed no clear differences in their properties. Herein these nanoparticles are compared on the basis of a fluorene co-polymer and its corresponding small molecule. Both systems formed nanoparticles with the same diameter, whereas the fluorescence properties clearly differed. In case of the polymer the fluorescence diminished, whereas for the small molecules the fluorescence increased. In addition, the capability of encapsulation and release of a hydrophobic dye from the fluorescent nanoparticles was studied. For the polymer system, encapsulation was highly efficient and no release was observed, whereas for the small molecule system encapsulation was less efficient and release of the dye was observed. These studies show a clear difference between small molecules and polymers which has important implications for the design of fluorescent nanoparticles.
LanguageEnglish
Pages10928-10934
JournalChemistry : A European Journal
Volume19
Issue number33
DOIs
StatePublished - 2013

Fingerprint

Conjugated polymers
Polymers
Nanoparticles
Molecules
Encapsulation
Fluorescence
Fluorescent Dyes
Coloring Agents

Cite this

@article{c83db1c6c71644babbead20306850f5a,
title = "Fluorescent π-conjugated polymer dots versus self-assembled small molecule nanoparticles : what’s the difference?",
abstract = "Fluorescent nanoparticles based on p-conjugated small molecules and polymers are two different classes of p-conjugated systems that have attracted much interest. To date, both emerging classes have only been studied separately and showed no clear differences in their properties. Herein these nanoparticles are compared on the basis of a fluorene co-polymer and its corresponding small molecule. Both systems formed nanoparticles with the same diameter, whereas the fluorescence properties clearly differed. In case of the polymer the fluorescence diminished, whereas for the small molecules the fluorescence increased. In addition, the capability of encapsulation and release of a hydrophobic dye from the fluorescent nanoparticles was studied. For the polymer system, encapsulation was highly efficient and no release was observed, whereas for the small molecule system encapsulation was less efficient and release of the dye was observed. These studies show a clear difference between small molecules and polymers which has important implications for the design of fluorescent nanoparticles.",
author = "I. Fischer and A.G. Kaeser and M.A.M. Peters-Gumbs and A.P.H.J. Schenning",
year = "2013",
doi = "10.1002/chem.201301258",
language = "English",
volume = "19",
pages = "10928--10934",
journal = "Chemistry : A European Journal",
issn = "0947-6539",
publisher = "Wiley-VCH Verlag",
number = "33",

}

Fluorescent π-conjugated polymer dots versus self-assembled small molecule nanoparticles : what’s the difference? / Fischer, I.; Kaeser, A.G.; Peters-Gumbs, M.A.M.; Schenning, A.P.H.J.

In: Chemistry : A European Journal, Vol. 19, No. 33, 2013, p. 10928-10934.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Fluorescent π-conjugated polymer dots versus self-assembled small molecule nanoparticles : what’s the difference?

AU - Fischer,I.

AU - Kaeser,A.G.

AU - Peters-Gumbs,M.A.M.

AU - Schenning,A.P.H.J.

PY - 2013

Y1 - 2013

N2 - Fluorescent nanoparticles based on p-conjugated small molecules and polymers are two different classes of p-conjugated systems that have attracted much interest. To date, both emerging classes have only been studied separately and showed no clear differences in their properties. Herein these nanoparticles are compared on the basis of a fluorene co-polymer and its corresponding small molecule. Both systems formed nanoparticles with the same diameter, whereas the fluorescence properties clearly differed. In case of the polymer the fluorescence diminished, whereas for the small molecules the fluorescence increased. In addition, the capability of encapsulation and release of a hydrophobic dye from the fluorescent nanoparticles was studied. For the polymer system, encapsulation was highly efficient and no release was observed, whereas for the small molecule system encapsulation was less efficient and release of the dye was observed. These studies show a clear difference between small molecules and polymers which has important implications for the design of fluorescent nanoparticles.

AB - Fluorescent nanoparticles based on p-conjugated small molecules and polymers are two different classes of p-conjugated systems that have attracted much interest. To date, both emerging classes have only been studied separately and showed no clear differences in their properties. Herein these nanoparticles are compared on the basis of a fluorene co-polymer and its corresponding small molecule. Both systems formed nanoparticles with the same diameter, whereas the fluorescence properties clearly differed. In case of the polymer the fluorescence diminished, whereas for the small molecules the fluorescence increased. In addition, the capability of encapsulation and release of a hydrophobic dye from the fluorescent nanoparticles was studied. For the polymer system, encapsulation was highly efficient and no release was observed, whereas for the small molecule system encapsulation was less efficient and release of the dye was observed. These studies show a clear difference between small molecules and polymers which has important implications for the design of fluorescent nanoparticles.

U2 - 10.1002/chem.201301258

DO - 10.1002/chem.201301258

M3 - Article

VL - 19

SP - 10928

EP - 10934

JO - Chemistry : A European Journal

T2 - Chemistry : A European Journal

JF - Chemistry : A European Journal

SN - 0947-6539

IS - 33

ER -