Fiber tracking in newborns with perinatal hypoxic-ischemia at birth and at 3 months

C. van Pul, J. Op den Buijs, Anna Vilanova, F.G. Roos, P.F.F. Wijn

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

The purpose of our study was to retrospectively investigate the feasibility of using fiber tracking to detect disturbances in white matter development in newborns suffering from hypoxic-ischemia, at birth and at the age of 3 months. Diffusion Tensor Images were obtained from full-term newborns, 7 with normal MRI and 10 with pathology related to perinatal hypoxic-ischemia. All parents gave informed consent. Visualization of white matter tracts was investigated using a volume tracing and quantification technique. Fiber tracking was useful to study the neonatal brain. Pathology resulted in different fiber patterns, compared to normal. Frequently affected were the corona radiata fibers.
Original languageEnglish
Pages (from-to)203-214
Number of pages12
JournalRadiology
Volume240
Issue number1
Publication statusPublished - 2006

Fingerprint

Dive into the research topics of 'Fiber tracking in newborns with perinatal hypoxic-ischemia at birth and at 3 months'. Together they form a unique fingerprint.

Cite this