The purpose of our study was to retrospectively investigate the feasibility of using fiber tracking to detect disturbances in white matter development in newborns suffering from hypoxic-ischemia, at birth and at the age of 3 months. Diffusion Tensor Images were obtained from full-term newborns, 7 with normal MRI and 10 with pathology related to perinatal hypoxic-ischemia. All parents gave informed consent. Visualization of white matter tracts was investigated using a volume tracing and quantification technique. Fiber tracking was useful to study the neonatal brain. Pathology resulted in different fiber patterns, compared to normal. Frequently affected were the corona radiata fibers.
|Number of pages||12|
|Publication status||Published - 2006|