Feasibility of diffusion tensor imaging (DTI) with fibre tractography of the normal female pelvic floor

F.M. Zijta, M. Froeling, M.P. Paardt, van der, M.M. Lakeman, S. Bipat, A.D. Swijndregt, van, G.J. Strijkers, A.J. Nederveen, J. Stoker

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Abstract

OBJECTIVES: To prospectively determine the feasibility of diffusion tensor imaging (DTI) with fibre tractography as a tool for the three-dimensional (3D) visualisation of normal pelvic floor anatomy. METHODS: Five young female nulliparous subjects (mean age 28 ± 3 years) underwent DTI at 3.0T. Two-dimensional diffusion-weighted axial spin-echo echo-planar (SP-EPI) pulse sequence of the pelvic floor was performed, with additional T2-TSE multiplanar sequences for anatomical reference. Fibre tractography for visualisation of predefined pelvic floor and pelvic wall muscles was performed offline by two observers, applying a consensus method. Three eigenvalues (¿1, ¿2, ¿3), fractional anisotropy (FA) and mean diffusivity (MD) were calculated from the fibre trajectories. RESULTS: In all subjects fibre tractography resulted in a satisfactory anatomical representation of the pubovisceral muscle, perineal body, anal - and urethral sphincter complex and internal obturator muscle. Mean FA values ranged from 0.23 ± 0.02 to 0.30 ± 0.04, MD values from 1.30 ± 0.08 to 1.73 ± 0.12 × 10(-)³ mm²/s. Muscular structures in the superficial layer of the pelvic floor could not be satisfactorily identified. CONCLUSIONS: This study demonstrates the feasibility of visualising the complex three-dimensional pelvic floor architecture using 3T-DTI with fibre tractography. DTI of the deep female pelvic floor may provide new insights into pelvic floor disorders.
Original languageEnglish
Pages (from-to)1243-1249
Number of pages7
JournalEuropean Radiology
Volume21
Issue number6
DOIs
Publication statusPublished - 2011

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    Zijta, F. M., Froeling, M., Paardt, van der, M. P., Lakeman, M. M., Bipat, S., Swijndregt, van, A. D., Strijkers, G. J., Nederveen, A. J., & Stoker, J. (2011). Feasibility of diffusion tensor imaging (DTI) with fibre tractography of the normal female pelvic floor. European Radiology, 21(6), 1243-1249. https://doi.org/10.1007/s00330-010-2044-8