Hydroaminomethylation of 1-octene and piperidine has been carried out using a pyrrole-substituted phosphine ligand (see Scheme; L), giving extremely high activities (TOF6200 h-1) and selectivities (linear/branched ratios>200). Acidic alcohols in the solvent mixture lead to higher activities but lower selectivities, whereas less acidic alcohols give extraordinarily good selectivities.
Hamers, B., Kosciusko-Morizet, E., Müller, C., & Vogt, D. (2009). Fast and selective hydroaminomethylation using xanthene-based amino-functionalized ligands. ChemCatChem, 1(1), 103-106. https://doi.org/10.1002/cctc.200900088