False-negative myocardial scintigraphy in balanced three-vessel disease, revealed by coronary pressure measurement

Wilbert H. Aarnoudse; Kees-Joost B.M. Botman; Nico H.J. Pijls

doi:10.1080/14628840310003244

False-negative myocardial scintigraphy in balanced three-vessel disease, revealed by coronary pressure measurement

Wilbert H. Aarnoudse, Kees-Joost B.M. Botman, Nico H.J. Pijls

Research output: Contribution to journal › Article › Academic › peer-review

56 Citations (Scopus)

Abstract

In nuclear perfusion imaging of the myocardium, a false-negative test result in patients with balanced three-vessel disease is a well-known pitfall. This paper describes a patient with typical chest pain and a negative myocardial perfusion scintigram. At coronary angiography, intermediate stenoses in the left anterior descending (LAD), left circumflex (LCX), and right coronary (RCA) arteries were present. Fractional flow reserve, measured by coronary pressure measurement, was 0.54, 0.56, and 0.66 respectively for the LAD, LCX, and RCA, unequivocally demonstrating the presence of balanced three-vessel disease. The patient underwent successful bypass surgery and remained event-free thereafter.

Original language	English
Pages (from-to)	67-71
Number of pages	5
Journal	International Journal of Cardiovascular Interventions
Volume	5
Issue number	2
DOIs	https://doi.org/10.1080/14628840310003244
Publication status	Published - 2 Jun 2003

Keywords

Balanced three-vessel disease
Coronary angiography
Coronary pressure measurement
Fractional flow reserve
Myocardial perfusion scintigraphy

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abstract = "In nuclear perfusion imaging of the myocardium, a false-negative test result in patients with balanced three-vessel disease is a well-known pitfall. This paper describes a patient with typical chest pain and a negative myocardial perfusion scintigram. At coronary angiography, intermediate stenoses in the left anterior descending (LAD), left circumflex (LCX), and right coronary (RCA) arteries were present. Fractional flow reserve, measured by coronary pressure measurement, was 0.54, 0.56, and 0.66 respectively for the LAD, LCX, and RCA, unequivocally demonstrating the presence of balanced three-vessel disease. The patient underwent successful bypass surgery and remained event-free thereafter.",

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AB - In nuclear perfusion imaging of the myocardium, a false-negative test result in patients with balanced three-vessel disease is a well-known pitfall. This paper describes a patient with typical chest pain and a negative myocardial perfusion scintigram. At coronary angiography, intermediate stenoses in the left anterior descending (LAD), left circumflex (LCX), and right coronary (RCA) arteries were present. Fractional flow reserve, measured by coronary pressure measurement, was 0.54, 0.56, and 0.66 respectively for the LAD, LCX, and RCA, unequivocally demonstrating the presence of balanced three-vessel disease. The patient underwent successful bypass surgery and remained event-free thereafter.

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False-negative myocardial scintigraphy in balanced three-vessel disease, revealed by coronary pressure measurement

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Keywords

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