Exploration of biosynthetic access to the shared precursor of the fusicoccane diterpenoid family

Julia Arens; Benedikt Engels; Stephan Klopries; Stefan Jennewein; Christian Ottmann; Frank Schulz

doi:10.1039/C2CC37154E

Exploration of biosynthetic access to the shared precursor of the fusicoccane diterpenoid family

Julia Arens
, Benedikt Engels
, Stephan Klopries
, Stefan Jennewein
, Christian Ottmann
, Frank Schulz

Chemical Biology

Research output: Contribution to journal › Article › Academic › peer-review

16 Citations (Scopus)

Abstract

Herein preparative scale access to the shared precursor of the fusicoccane family of diterpenoids through biosynthesis in three different microbial hosts is reported. A method to purify the metabolite in high purity and on a preparative scale was explored.

Original language	English
Pages (from-to)	4337-4339
Number of pages	3
Journal	Chemical Communications, ChemComm
Volume	49
Issue number	39
DOIs	https://doi.org/10.1039/C2CC37154E
Publication status	Published - 14 May 2013

Keywords

Alternaria/enzymology
Biocatalysis
Cladosporium/metabolism
Diterpenes/chemistry
Fungal Proteins/genetics
Hemiterpenes/chemistry
Organophosphorus Compounds/chemistry

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10.1039/C2CC37154E

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title = "Exploration of biosynthetic access to the shared precursor of the fusicoccane diterpenoid family",

abstract = "Herein preparative scale access to the shared precursor of the fusicoccane family of diterpenoids through biosynthesis in three different microbial hosts is reported. A method to purify the metabolite in high purity and on a preparative scale was explored.",

keywords = "Alternaria/enzymology, Biocatalysis, Cladosporium/metabolism, Diterpenes/chemistry, Fungal Proteins/genetics, Hemiterpenes/chemistry, Organophosphorus Compounds/chemistry",

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AU - Arens, Julia

AU - Engels, Benedikt

AU - Klopries, Stephan

AU - Jennewein, Stefan

AU - Ottmann, Christian

AU - Schulz, Frank

PY - 2013/5/14

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KW - Alternaria/enzymology

KW - Biocatalysis

KW - Cladosporium/metabolism

KW - Diterpenes/chemistry

KW - Fungal Proteins/genetics

KW - Hemiterpenes/chemistry

KW - Organophosphorus Compounds/chemistry

U2 - 10.1039/C2CC37154E

DO - 10.1039/C2CC37154E

M3 - Article

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JO - Chemical Communications, ChemComm

JF - Chemical Communications, ChemComm

IS - 39

ER -

Exploration of biosynthetic access to the shared precursor of the fusicoccane diterpenoid family

Abstract

Keywords

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