Evaluation of the heamodynamic characteristics of drug-eluting stents at implantation and at follow-up

M. Veer, van 't, N.H.J. Pijls, W.H. Aarnoudse, J.J. (Jacques) Koolen, F.N. Vosse, van de

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Abstract

AIMS: The aim of this study was to investigate the physiologic parameters: fractional flow reserve (FFR), hyperaemic trans-stent gradient (HTG), and wall shear stress (WSS) at implantation and at 6-month follow-up in the drug-eluting sirolimus stent and in its bare metal counterpart implanted in pairs within the same patient. METHODS AND RESULTS: Twenty patients, accepted for percutaneous coronary intervention of at least two coronary arteries with comparable vessel and stenosis characteristics, received at random one sirolimus-eluting stent and one bare metal stent (BMS). Coronary pressure, FFR, HTG, and WSS were measured just after stent implantation and at 6-month follow-up. At 6-month follow-up, FFR was significantly higher in the sirolimus group compared with the bare metal group (0.91+/-0.05 vs. 0.83+/-0.10, P=0.027) and HTG was significantly lower (1.2+/-1.2 vs. 7.5+/-8.1 mmHg, P
Original languageEnglish
Pages (from-to)1811-1817
JournalEuropean Heart Journal
Volume27
Issue number15
DOIs
Publication statusPublished - 2006

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