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Evaluation of mixed-mode stationary phases in liquid chromatography for the separation of charged and uncharged oligomer-like model compounds

  • J.T. Eleveld
  • , H.A. Claessens
  • , J.L. Ammerdorffer
  • , A.M. Herk, van
  • , C.A. Cramers

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

The possibility to sep. charged and uncharged oligomer-like test compds. by high-performance liq. chromatog. was investigated, using mixed-mode (reversed-phase/anion-exchange) stationary phases. In order to examine this possibility, several columns were evaluated for their reversed-phase, anion-exchange and mixed-mode properties using neutral and charged model compds. The OmniPac PAX-500, the PRP-X100 and the mixed-phase PLRP-S/PL-SAX columns showed promising results for the sepn. of real samples. [on SciFinder (R)]
Original languageEnglish
Pages (from-to)211-227
Number of pages17
JournalJournal of Chromatography, A
Volume677
Issue number2
DOIs
Publication statusPublished - 1994

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