TY - JOUR
T1 - Evaluation of injection systems for open tubular liquid chromatography
AU - Claessens, H.A.
AU - Burcinova, A.
AU - Mussche, P.
AU - Tilburg, van, C.C.E.
AU - Cramers, C.A.
PY - 1990
Y1 - 1990
N2 - The main advantages of open tubular liquid chromatography (OTLC) over conventional packed-column liquid chromatography are the gain in resolution and the increased permeability. At present the reproducible preparation of narrow-bore columns and the lack of suitable commercial chromatographic equipment delay the development of OTLC. There are stringent requirements for injectors and detectors for OTLC with respect to their volumes, geometry, and contributions to the total band broadening. In this work some properties of two different sampling systems for OTLC were studied with respect to the accuracy and repeatability of the injected volumes. An approach is presented and discussed to determine the profile factors of these injection systems.
AB - The main advantages of open tubular liquid chromatography (OTLC) over conventional packed-column liquid chromatography are the gain in resolution and the increased permeability. At present the reproducible preparation of narrow-bore columns and the lack of suitable commercial chromatographic equipment delay the development of OTLC. There are stringent requirements for injectors and detectors for OTLC with respect to their volumes, geometry, and contributions to the total band broadening. In this work some properties of two different sampling systems for OTLC were studied with respect to the accuracy and repeatability of the injected volumes. An approach is presented and discussed to determine the profile factors of these injection systems.
U2 - 10.1002/mcs.1220020309
DO - 10.1002/mcs.1220020309
M3 - Article
VL - 2
SP - 132
EP - 137
JO - Journal of Microcolumn Separations
JF - Journal of Microcolumn Separations
SN - 1040-7685
IS - 3
ER -