Estimation of the instrumental band broadening contribution to the column elution profiles in open tubular capillary liquid chromatography

H.A. Claessens, M.J.J. Hetem, P.A. Leclercq, C.A.M.G. Cramers

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

Abstract

In comparison with conventionally packed HPLC columns from a theoretical point of view, open capillary liquid chromatography (OTLC) systems offer a number of advantages like high plate numbers and short analysis times. Contrary to this are the drastic changes to be made to the instrumentation. Especially the contribution to the band broadening by the chromatographic equipment must be considerably reduced. In the present study an OTLC-system was developed and evaluated, which yields satisfactory results for 26 mu i.d. columns. The determination of the contribution of the chromatographic equipment to the total band broadening is discussed.
Original languageEnglish
Title of host publicationEighth International Symposium on Capillary Chromatography : Riva del Garda, Italy, May 19-21, 1987
EditorsP. Sandra
Place of PublicationHeidelberg
PublisherHuethig
Pages1130-1140
Volume2
Publication statusPublished - 1987
Event8th International Symposium on Capillary Chromatography, 1987 - Palazzo dei Congressi, Riva del Garda, Italy
Duration: 19 May 198721 May 1987

Conference

Conference8th International Symposium on Capillary Chromatography, 1987
CountryItaly
CityRiva del Garda
Period19/05/8721/05/87

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Liquid chromatography

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Claessens, H. A., Hetem, M. J. J., Leclercq, P. A., & Cramers, C. A. M. G. (1987). Estimation of the instrumental band broadening contribution to the column elution profiles in open tubular capillary liquid chromatography. In P. Sandra (Ed.), Eighth International Symposium on Capillary Chromatography : Riva del Garda, Italy, May 19-21, 1987 (Vol. 2, pp. 1130-1140). Heidelberg: Huethig.
Claessens, H.A. ; Hetem, M.J.J. ; Leclercq, P.A. ; Cramers, C.A.M.G. / Estimation of the instrumental band broadening contribution to the column elution profiles in open tubular capillary liquid chromatography. Eighth International Symposium on Capillary Chromatography : Riva del Garda, Italy, May 19-21, 1987. editor / P. Sandra. Vol. 2 Heidelberg : Huethig, 1987. pp. 1130-1140
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abstract = "In comparison with conventionally packed HPLC columns from a theoretical point of view, open capillary liquid chromatography (OTLC) systems offer a number of advantages like high plate numbers and short analysis times. Contrary to this are the drastic changes to be made to the instrumentation. Especially the contribution to the band broadening by the chromatographic equipment must be considerably reduced. In the present study an OTLC-system was developed and evaluated, which yields satisfactory results for 26 mu i.d. columns. The determination of the contribution of the chromatographic equipment to the total band broadening is discussed.",
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year = "1987",
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booktitle = "Eighth International Symposium on Capillary Chromatography : Riva del Garda, Italy, May 19-21, 1987",
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Claessens, HA, Hetem, MJJ, Leclercq, PA & Cramers, CAMG 1987, Estimation of the instrumental band broadening contribution to the column elution profiles in open tubular capillary liquid chromatography. in P Sandra (ed.), Eighth International Symposium on Capillary Chromatography : Riva del Garda, Italy, May 19-21, 1987. vol. 2, Huethig, Heidelberg, pp. 1130-1140, 8th International Symposium on Capillary Chromatography, 1987, Riva del Garda, Italy, 19/05/87.

Estimation of the instrumental band broadening contribution to the column elution profiles in open tubular capillary liquid chromatography. / Claessens, H.A.; Hetem, M.J.J.; Leclercq, P.A.; Cramers, C.A.M.G.

Eighth International Symposium on Capillary Chromatography : Riva del Garda, Italy, May 19-21, 1987. ed. / P. Sandra. Vol. 2 Heidelberg : Huethig, 1987. p. 1130-1140.

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademic

TY - GEN

T1 - Estimation of the instrumental band broadening contribution to the column elution profiles in open tubular capillary liquid chromatography

AU - Claessens, H.A.

AU - Hetem, M.J.J.

AU - Leclercq, P.A.

AU - Cramers, C.A.M.G.

PY - 1987

Y1 - 1987

N2 - In comparison with conventionally packed HPLC columns from a theoretical point of view, open capillary liquid chromatography (OTLC) systems offer a number of advantages like high plate numbers and short analysis times. Contrary to this are the drastic changes to be made to the instrumentation. Especially the contribution to the band broadening by the chromatographic equipment must be considerably reduced. In the present study an OTLC-system was developed and evaluated, which yields satisfactory results for 26 mu i.d. columns. The determination of the contribution of the chromatographic equipment to the total band broadening is discussed.

AB - In comparison with conventionally packed HPLC columns from a theoretical point of view, open capillary liquid chromatography (OTLC) systems offer a number of advantages like high plate numbers and short analysis times. Contrary to this are the drastic changes to be made to the instrumentation. Especially the contribution to the band broadening by the chromatographic equipment must be considerably reduced. In the present study an OTLC-system was developed and evaluated, which yields satisfactory results for 26 mu i.d. columns. The determination of the contribution of the chromatographic equipment to the total band broadening is discussed.

M3 - Conference contribution

VL - 2

SP - 1130

EP - 1140

BT - Eighth International Symposium on Capillary Chromatography : Riva del Garda, Italy, May 19-21, 1987

A2 - Sandra, P.

PB - Huethig

CY - Heidelberg

ER -

Claessens HA, Hetem MJJ, Leclercq PA, Cramers CAMG. Estimation of the instrumental band broadening contribution to the column elution profiles in open tubular capillary liquid chromatography. In Sandra P, editor, Eighth International Symposium on Capillary Chromatography : Riva del Garda, Italy, May 19-21, 1987. Vol. 2. Heidelberg: Huethig. 1987. p. 1130-1140