Background: Prevalence of mite allergy continues to rise in most European countries. Long-lasting clinical benefit asks for lifelong allergen avoidance. The allergic reaction towards products of the mites is an immediate reaction that may be located in the lungs (asthma), the nose (rhinitis) or the skin (atopic dermatitis). The mites live in homes with a suitable indoor climate. This connects the mite allergy problem to indoor environmental quality as described in the domain of building physics. Earlier research has defined general biological threshold levels for sensitization and symptom development in mite allergy, and these levels have been related to environmental characteristics. However, more recent epidemiologic studies suggest that sensitization to mite products may take place even below these defined hygienic levels. For the relationship between environmental characteristics and mite allergen levels consensus has been lost. A meta-analysis of all controlled trials on mite allergen reduction levels by environmental means showed no clinical benefit. Apparently a more tailored guidance is needed for the well-being of those affected with mite allergy. This calls for a personalized management system of environmental means in patient practice. Aim of research: Developing an environmental methodology to monitor the critical control points for (mite)allergen levels in dwellings, incorporating both building physics performance and the life style in the inhabitants. Results so far indicate that robust algorithms are feasible to guide the monitoring and control process.
|Title of host publication||PhD research projects|
|Editors||E. Blokhuis, C. Hopfe, M. Verhoeven|
|Place of Publication||Eindhoven|
|Publisher||Technische Universiteit Eindhoven|
|Publication status||Published - 2007|