Enhanced selectivity for the hydrolysis of block copoly(2-oxazoline)s in ethanol-water resulting in linear poly(ethylene imine) copolymers

H.P.C. Kuringen, van, V.R. Rosa, de la, M.W.M. Fijten, J.P.A. Heuts, R. Hoogenboom

Research output: Contribution to journalArticleAcademicpeer-review

22 Citations (Scopus)
2 Downloads (Pure)

Abstract

The ability of merging the properties of poly(2-oxazoline)s and poly(ethylene imine) is of high interest for various biomedical applications, including gene delivery, biosensors, and switchable surfaces and nanoparticles. In the present research, a methodology for the controlled and selective hydrolysis of (co)poly(2-oxazoline)s is developed in an ethanol–water solvent mixture, opening the path toward a wide range of block poly(2-oxazoline-co-ethylene imine) (POx-PEI) copolymers with tunable properties. The unexpected influence of the selected ethanol–water binary solvent mixture on the hydrolysis kinetics and selectivity is highlighted in the pursue of well-defined POx-PEI block copolymers
Original languageEnglish
Pages (from-to)827-832
Number of pages6
JournalMacromolecular Rapid Communications
Volume33
Issue number9
DOIs
Publication statusPublished - 2012

Fingerprint

Dive into the research topics of 'Enhanced selectivity for the hydrolysis of block copoly(2-oxazoline)s in ethanol-water resulting in linear poly(ethylene imine) copolymers'. Together they form a unique fingerprint.

Cite this