Engineering protein switches : sensors, regulators, and spare parts for biology and biotechnology

M.V. Golynskiy, M.S.T. Koay, J.L. Vinkenborg, M. Merkx

Research output: Contribution to journalArticleAcademicpeer-review

38 Citations (Scopus)
1 Downloads (Pure)

Abstract

Switch protein switch! Proteins that switch between distinct conformational states are ideal for monitoring and controlling molecular processes in biological systems. We discuss new engineering concepts for the construction of protein switches that have the potential to be generally applicable and discuss them according to their mechanism of action.
Original languageEnglish
Pages (from-to)353-361
Number of pages9
JournalChemBioChem
Volume12
Issue number3
DOIs
Publication statusPublished - 2011

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