Abstract
Dendrimers with end-groups of defined chiral composition have been prepared from alkyne functional enantio-pure building blocks obtained by selective enzymatic (ADH) ketone reductions using click chemistry. Optical rotation and enantioselective enzymatic modification is in agreement with the chiral composition of the dendrimers and permits unique molecular-level encoding of stereoisomeric dendritic libraries.
Original language | English |
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Pages (from-to) | 9870-9872 |
Journal | Chemical Communications |
Volume | 47 |
Issue number | 35 |
DOIs | |
Publication status | Published - 2011 |