Encoded dendrimers with defined chiral composition via 'click' reaction of enantiopure building blocks

B. Yeniad, H. Naik, R.J. Amir, C.E. Koning, C.J. Hawker, A. Heise

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

Abstract

Dendrimers with end-groups of defined chiral composition have been prepared from alkyne functional enantio-pure building blocks obtained by selective enzymatic (ADH) ketone reductions using click chemistry. Optical rotation and enantioselective enzymatic modification is in agreement with the chiral composition of the dendrimers and permits unique molecular-level encoding of stereoisomeric dendritic libraries.
Original languageEnglish
Pages (from-to)9870-9872
JournalChemical Communications
Volume47
Issue number35
DOIs
Publication statusPublished - 2011

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    Yeniad, B., Naik, H., Amir, R. J., Koning, C. E., Hawker, C. J., & Heise, A. (2011). Encoded dendrimers with defined chiral composition via 'click' reaction of enantiopure building blocks. Chemical Communications, 47(35), 9870-9872. https://doi.org/10.1039/c1cc12434j