Encapsulation and release by star-shaped block copolymers as unimolecular nanocontainers

D. Kul; L.M. Renterghem, van; M.A.R. Meier; S. Strandman; H. Tenhu; S.S. Yilmaz; U.S. Schubert; F.E. Du Prez

doi:10.1002/pola.22413

Encapsulation and release by star-shaped block copolymers as unimolecular nanocontainers

D. Kul
, L.M. Renterghem, van
, M.A.R. Meier
, S. Strandman
, H. Tenhu
, S.S. Yilmaz
, U.S. Schubert
, F.E. Du Prez

Chemical Engineering and Chemistry

Research output: Contribution to journal › Article › Academic › peer-review

30 Citations (Scopus)

Abstract

Five-arm star-shaped poly(ethylene oxide) (PEO) with terminal bromide groups was used as a macroinitiator for the atom transfer radical polymerization of tert-butyl acrylate (tBA), resulting in five-arm star-shaped poly(ethylene oxide)-block-poly(tert-butyl acrylate) block copolymers. The polymerization proceeded in a controlled way using a copper(I)bromide/pentamethyl diethylenetriamine catalytic system in acetonitrile as solvent. The hydrolysis of the tBA blocks of the amphiphilic star-shaped PEO-b-PtBA block copolymer resulted in dihydrophilic star structures. The encapsulation of the star-block copolymers and their release properties in acid environment have been followed by UV-spectroscopy and color changes, using the dye methyl orange as a hydrophilic guest molecule. Characterization of the structures has been done by 1H NMR, size exclusion chromatography, MALDI-TOF, and differential scanning calorimetry. © 2007 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 46: 650-660, 2008

Original language	English
Pages (from-to)	650-660
Journal	Journal of Polymer Science, Part A: Polymer Chemistry
Volume	46
Issue number	2
DOIs	https://doi.org/10.1002/pola.22413
Publication status	Published - 2008

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10.1002/pola.22413

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title = "Encapsulation and release by star-shaped block copolymers as unimolecular nanocontainers",

abstract = "Five-arm star-shaped poly(ethylene oxide) (PEO) with terminal bromide groups was used as a macroinitiator for the atom transfer radical polymerization of tert-butyl acrylate (tBA), resulting in five-arm star-shaped poly(ethylene oxide)-block-poly(tert-butyl acrylate) block copolymers. The polymerization proceeded in a controlled way using a copper(I)bromide/pentamethyl diethylenetriamine catalytic system in acetonitrile as solvent. The hydrolysis of the tBA blocks of the amphiphilic star-shaped PEO-b-PtBA block copolymer resulted in dihydrophilic star structures. The encapsulation of the star-block copolymers and their release properties in acid environment have been followed by UV-spectroscopy and color changes, using the dye methyl orange as a hydrophilic guest molecule. Characterization of the structures has been done by 1H NMR, size exclusion chromatography, MALDI-TOF, and differential scanning calorimetry. {\textcopyright} 2007 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 46: 650-660, 2008",

author = "D. Kul and \{Renterghem, van\}, L.M. and M.A.R. Meier and S. Strandman and H. Tenhu and S.S. Yilmaz and U.S. Schubert and \{Du Prez\}, F.E.",

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journal = "Journal of Polymer Science, Part A: Polymer Chemistry",

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AU - Kul, D.

AU - Renterghem, van, L.M.

AU - Meier, M.A.R.

AU - Strandman, S.

AU - Tenhu, H.

AU - Yilmaz, S.S.

AU - Schubert, U.S.

AU - Du Prez, F.E.

PY - 2008

Y1 - 2008

N2 - Five-arm star-shaped poly(ethylene oxide) (PEO) with terminal bromide groups was used as a macroinitiator for the atom transfer radical polymerization of tert-butyl acrylate (tBA), resulting in five-arm star-shaped poly(ethylene oxide)-block-poly(tert-butyl acrylate) block copolymers. The polymerization proceeded in a controlled way using a copper(I)bromide/pentamethyl diethylenetriamine catalytic system in acetonitrile as solvent. The hydrolysis of the tBA blocks of the amphiphilic star-shaped PEO-b-PtBA block copolymer resulted in dihydrophilic star structures. The encapsulation of the star-block copolymers and their release properties in acid environment have been followed by UV-spectroscopy and color changes, using the dye methyl orange as a hydrophilic guest molecule. Characterization of the structures has been done by 1H NMR, size exclusion chromatography, MALDI-TOF, and differential scanning calorimetry. © 2007 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 46: 650-660, 2008

AB - Five-arm star-shaped poly(ethylene oxide) (PEO) with terminal bromide groups was used as a macroinitiator for the atom transfer radical polymerization of tert-butyl acrylate (tBA), resulting in five-arm star-shaped poly(ethylene oxide)-block-poly(tert-butyl acrylate) block copolymers. The polymerization proceeded in a controlled way using a copper(I)bromide/pentamethyl diethylenetriamine catalytic system in acetonitrile as solvent. The hydrolysis of the tBA blocks of the amphiphilic star-shaped PEO-b-PtBA block copolymer resulted in dihydrophilic star structures. The encapsulation of the star-block copolymers and their release properties in acid environment have been followed by UV-spectroscopy and color changes, using the dye methyl orange as a hydrophilic guest molecule. Characterization of the structures has been done by 1H NMR, size exclusion chromatography, MALDI-TOF, and differential scanning calorimetry. © 2007 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 46: 650-660, 2008

U2 - 10.1002/pola.22413

DO - 10.1002/pola.22413

M3 - Article

SN - 0887-624X

VL - 46

SP - 650

EP - 660

JO - Journal of Polymer Science, Part A: Polymer Chemistry

JF - Journal of Polymer Science, Part A: Polymer Chemistry

IS - 2

ER -

Encapsulation and release by star-shaped block copolymers as unimolecular nanocontainers

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