Encapsulation and release by star-shaped block copolymers as unimolecular nanocontainers

D. Kul, L.M. Renterghem, van, M.A.R. Meier, S. Strandman, H. Tenhu, S.S. Yilmaz, U.S. Schubert, F.E. Du Prez

Research output: Contribution to journalArticleAcademicpeer-review

30 Citations (Scopus)

Abstract

Five-arm star-shaped poly(ethylene oxide) (PEO) with terminal bromide groups was used as a macroinitiator for the atom transfer radical polymerization of tert-butyl acrylate (tBA), resulting in five-arm star-shaped poly(ethylene oxide)-block-poly(tert-butyl acrylate) block copolymers. The polymerization proceeded in a controlled way using a copper(I)bromide/pentamethyl diethylenetriamine catalytic system in acetonitrile as solvent. The hydrolysis of the tBA blocks of the amphiphilic star-shaped PEO-b-PtBA block copolymer resulted in dihydrophilic star structures. The encapsulation of the star-block copolymers and their release properties in acid environment have been followed by UV-spectroscopy and color changes, using the dye methyl orange as a hydrophilic guest molecule. Characterization of the structures has been done by 1H NMR, size exclusion chromatography, MALDI-TOF, and differential scanning calorimetry. © 2007 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 46: 650-660, 2008
Original languageEnglish
Pages (from-to)650-660
JournalJournal of Polymer Science, Part A: Polymer Chemistry
Volume46
Issue number2
DOIs
Publication statusPublished - 2008

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