TY - GEN
T1 - Elements of RAFT navigation
T2 - RAFT 20 years later: RAFT-synthesis of uniform, sequence-defined (co)polymers
AU - Haven, Joris J.
AU - Hendrikx, Matthew
AU - Junkers, Tanja
AU - Leenaers, Pieter J.
AU - Tsompanoglou, Theodora
AU - Boyer, Cyrille
AU - Xu, Jiangtao
AU - Postma, Almar
AU - Moad, Graeme
PY - 2018/1/1
Y1 - 2018/1/1
N2 - This paper focuses on one of the next directions in the evolution of reversible addition-fragmentation (RAFT) polymerization, namely, progress towards the synthesis of discrete or uniform, sequence-defined (co)polymers. Following a brief review of RAFT-single unit monomer insertion (RAFT-SUMI), we describe recent developments in the field. We point to difficulties in achieving consecutive RAFT-SUMI and report two strategies for overcoming the issue of initiator-derived by-products. We show that the selection of RAFT agent is critical in selective RAFT-SUMI of N,N-dimethylacrylamide (DMAm) into a trithiocarbonate in aqueous solution. Finally we recount on the use of photoRAFT- or PET-RAFT-SUMI in the high yield synthesis of discrete oligomers comprising two or more consecutive SUMI steps.
AB - This paper focuses on one of the next directions in the evolution of reversible addition-fragmentation (RAFT) polymerization, namely, progress towards the synthesis of discrete or uniform, sequence-defined (co)polymers. Following a brief review of RAFT-single unit monomer insertion (RAFT-SUMI), we describe recent developments in the field. We point to difficulties in achieving consecutive RAFT-SUMI and report two strategies for overcoming the issue of initiator-derived by-products. We show that the selection of RAFT agent is critical in selective RAFT-SUMI of N,N-dimethylacrylamide (DMAm) into a trithiocarbonate in aqueous solution. Finally we recount on the use of photoRAFT- or PET-RAFT-SUMI in the high yield synthesis of discrete oligomers comprising two or more consecutive SUMI steps.
UR - http://www.scopus.com/inward/record.url?scp=85052797437&partnerID=8YFLogxK
U2 - 10.1021/bk-2018-1284.ch004
DO - 10.1021/bk-2018-1284.ch004
M3 - Conference contribution
AN - SCOPUS:85052797437
SN - 9780841233188
T3 - ACS Symposium Series
SP - 77
EP - 103
BT - Reversible Deactivation Radical Polymerization
A2 - Tsarevsky, Nicolay V.
A2 - Gao, Haifeng
A2 - Matyjaszewski, Krzysztof
A2 - Sumerlin, Brent S.
PB - American Chemical Society
CY - Washington, DC
ER -