Elastic demons : characterizing cortical development in neonates using an implicit surface registration

P.C. Pearlman, I. Išgum, K.J. Kersbergen, M.J.N.L. Benders, M.A. Viergever, J.P.W. Pluim

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

1 Citation (Scopus)

Abstract

We present an approach for nonrigid registration of consecutive neonatal cortical surfaces from MR images acquired at 30 and 40 week corrected gestational ages. Surfaces are registered implicitly using a method based on the Demons algorithm. Our key innovation is removing the Gaussian smoothing term in Demons in favor of an elasticity constraint that simultaneously promotes more realistic deformations and smooths the deformation field. This is advantageous because the constraint smooths the deformation field along the surface rather than across it. Therefore, fine deformations, such as those necessary to characterize small, new cortical folds, are preserved. The estimated deformation fields are then used to characterize brain development. © 2012 Springer-Verlag.
Original languageEnglish
Title of host publication2nd International Workshop on Spatiotemporal Image Analysis for Longitudinal and Time-Series Image Data, STIA 2012
EditorsS. Durrleman
Place of PublicationBerlin
PublisherSpringer
Pages38-49
ISBN (Print)978-3-642-33555-6
DOIs
Publication statusPublished - 2012
Event2nd International Workshop on Spatiotemporal Image Analysis for Longitudinal and Time-Series Image Data (STIA 2012) - Nice, France
Duration: 1 Oct 20121 Oct 2012
Conference number: 2

Publication series

NameLecture Notes in Computer Science
Volume7570
ISSN (Print)0302-9743

Workshop

Workshop2nd International Workshop on Spatiotemporal Image Analysis for Longitudinal and Time-Series Image Data (STIA 2012)
Abbreviated titleSTIA 2012
CountryFrance
CityNice
Period1/10/121/10/12
OtherWorkshop held in conjunction with the 5th International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI 2012)

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