Effects of valve geometry and tissue anisotropy on the radial stretch and coaptation area of tissue-engineered heart valves

S. Loerakker, G. Argento, C.W.J. Oomens, F.P.T. Baaijens

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

Abstract

Tissue engineering represents a promising technique to overcome the limitations of the current valve prostheses, since it allows for synthesizing living, autologous valves that have the potential to grow and remodel in response to changing demands. However, one particular problem with tissue-engineered heart valves (TEHVs) is retraction of the valve leaflets (Fig. 1), which results in valvular insufficiency [1, 2]. As long-term regurgitation will lead to ventricular failure, this is a critical problem that needs to be solved before TEHVs can be used in clinical practice.
Original languageEnglish
Title of host publicationASME 2013 Summer Bioengineering Conference, SBC 2013, 26-29 June 2013, Sunriver, Oregon
PublisherAmerican Society of Mechanical Engineers
Pages1-2
ISBN (Print)9780791855607
DOIs
Publication statusPublished - 2013
EventASME 2013 Summer Bioengineering Conference (SBC 2013) - Sunriver, United States
Duration: 26 Jun 201329 Jun 2013
http://www.asmeconferences.org/SBC2013/

Conference

ConferenceASME 2013 Summer Bioengineering Conference (SBC 2013)
Abbreviated titleSBC 2013
CountryUnited States
CitySunriver
Period26/06/1329/06/13
Internet address

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