Effectiveness, safety and efficacy of INTELLiVENT–adaptive support ventilation, a closed–loop ventilation mode for use in ICU patients–a systematic review

M. Botta; E.F.E. Wenstedt; A.M. Tsonas; L.A. Buiteman-Kruizinga; D.M.P. van Meenen; H.H.M. Korsten; J. Horn; F. Paulus; A.G.J.H. Bindels; M.J. Schultz; A.J.R. de Bie

doi:10.1080/17476348.2021.1933450

Effectiveness, safety and efficacy of INTELLiVENT–adaptive support ventilation, a closed–loop ventilation mode for use in ICU patients–a systematic review

M. Botta (Corresponding author)
, E.F.E. Wenstedt
, A.M. Tsonas
, L.A. Buiteman-Kruizinga
, D.M.P. van Meenen
, H.H.M. Korsten
, J. Horn
, F. Paulus
, A.G.J.H. Bindels
, M.J. Schultz
, A.J.R. de Bie

Research output: Contribution to journal › Article › Academic › peer-review

26 Citations (Scopus)

135 Downloads (Pure)

Abstract

Introduction: INTELLiVENT–Adaptive Support Ventilation (INTELLiVENT–ASV), an advanced closed–loop ventilation mode for use in intensive care unit (ICU) patients, is equipped with algorithms that automatically adjust settings on the basis of physiologic signals and patient’s activity. Here we describe its effectiveness, safety, and efficacy in various types of ICU patients. Areas covered: A systematic search conducted in MEDLINE, EMBASE, the Cochrane Central register of Controlled Trials (CENTRAL), and in Google Scholar identified 10 randomized clinical trials. Expert opinion: Studies suggest INTELLiVENT–ASV to be an effective automated mode with regard to the titrations of tidal volume, airway pressure, and oxygen. INTELLiVENT–ASV is as safe as conventional modes. However, thus far studies have not shown INTELLiVENT–ASV to be superior to conventional modes with regard to duration of ventilation and other patient–centered outcomes. Future studies are needed to test its efficacy.

Original language	English
Pages (from-to)	1403-1413
Number of pages	11
Journal	Expert Review of Respiratory Medicine
Volume	15
Issue number	11
DOIs	https://doi.org/10.1080/17476348.2021.1933450
Publication status	Published - Nov 2021

Bibliographical note

Publisher Copyright:
© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

Funding

This paper was not funded. Manuscripts in Chinese were translated to English by Shan Nan (College of Biomedical Engineering and Instrumental Science, Zhejiang University, Hangzhou, China).

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Artificial ventilation
automated ventilation
closed–loop ventilation
effectiveness
efficacy
INTELLiVENT–ASV
intensive care unit
invasive ventilation
protective ventilation
safety
Intensive Care Units
Humans
Lung
Tidal Volume
Respiration, Artificial
Critical Care

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Botta, M., Wenstedt, E. F. E., Tsonas, A. M., Buiteman-Kruizinga, L. A., van Meenen, D. M. P., Korsten, H. H. M., Horn, J., Paulus, F., Bindels, A. G. J. H., Schultz, M. J., & de Bie, A. J. R. (2021). Effectiveness, safety and efficacy of INTELLiVENT–adaptive support ventilation, a closed–loop ventilation mode for use in ICU patients–a systematic review. Expert Review of Respiratory Medicine, 15(11), 1403-1413. https://doi.org/10.1080/17476348.2021.1933450

@article{fddcb2ead9404002b8a6a2b97f9c270d,

title = "Effectiveness, safety and efficacy of INTELLiVENT–adaptive support ventilation, a closed–loop ventilation mode for use in ICU patients–a systematic review",

abstract = "Introduction: INTELLiVENT–Adaptive Support Ventilation (INTELLiVENT–ASV), an advanced closed–loop ventilation mode for use in intensive care unit (ICU) patients, is equipped with algorithms that automatically adjust settings on the basis of physiologic signals and patient{\textquoteright}s activity. Here we describe its effectiveness, safety, and efficacy in various types of ICU patients. Areas covered: A systematic search conducted in MEDLINE, EMBASE, the Cochrane Central register of Controlled Trials (CENTRAL), and in Google Scholar identified 10 randomized clinical trials. Expert opinion: Studies suggest INTELLiVENT–ASV to be an effective automated mode with regard to the titrations of tidal volume, airway pressure, and oxygen. INTELLiVENT–ASV is as safe as conventional modes. However, thus far studies have not shown INTELLiVENT–ASV to be superior to conventional modes with regard to duration of ventilation and other patient–centered outcomes. Future studies are needed to test its efficacy.",

keywords = "Artificial ventilation, automated ventilation, closed–loop ventilation, effectiveness, efficacy, INTELLiVENT–ASV, intensive care unit, invasive ventilation, protective ventilation, safety, Intensive Care Units, Humans, Lung, Tidal Volume, Respiration, Artificial, Critical Care",

author = "M. Botta and E.F.E. Wenstedt and A.M. Tsonas and L.A. Buiteman-Kruizinga and \{van Meenen\}, D.M.P. and H.H.M. Korsten and J. Horn and F. Paulus and A.G.J.H. Bindels and M.J. Schultz and \{de Bie\}, A.J.R.",

note = "Publisher Copyright: {\textcopyright} 2021 The Author(s). Published by Informa UK Limited, trading as Taylor \& Francis Group.",

year = "2021",

month = nov,

doi = "10.1080/17476348.2021.1933450",

language = "English",

volume = "15",

pages = "1403--1413",

journal = "Expert Review of Respiratory Medicine",

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Botta, M, Wenstedt, EFE, Tsonas, AM, Buiteman-Kruizinga, LA, van Meenen, DMP, Korsten, HHM, Horn, J, Paulus, F, Bindels, AGJH, Schultz, MJ & de Bie, AJR 2021, 'Effectiveness, safety and efficacy of INTELLiVENT–adaptive support ventilation, a closed–loop ventilation mode for use in ICU patients–a systematic review', Expert Review of Respiratory Medicine, vol. 15, no. 11, pp. 1403-1413. https://doi.org/10.1080/17476348.2021.1933450

Effectiveness, safety and efficacy of INTELLiVENT–adaptive support ventilation, a closed–loop ventilation mode for use in ICU patients–a systematic review. / Botta, M. (Corresponding author); Wenstedt, E.F.E.; Tsonas, A.M. et al.
In: Expert Review of Respiratory Medicine, Vol. 15, No. 11, 11.2021, p. 1403-1413.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Effectiveness, safety and efficacy of INTELLiVENT–adaptive support ventilation, a closed–loop ventilation mode for use in ICU patients–a systematic review

AU - Botta, M.

AU - Wenstedt, E.F.E.

AU - Tsonas, A.M.

AU - Buiteman-Kruizinga, L.A.

AU - van Meenen, D.M.P.

AU - Korsten, H.H.M.

AU - Horn, J.

AU - Paulus, F.

AU - Bindels, A.G.J.H.

AU - Schultz, M.J.

AU - de Bie, A.J.R.

PY - 2021/11

Y1 - 2021/11

N2 - Introduction: INTELLiVENT–Adaptive Support Ventilation (INTELLiVENT–ASV), an advanced closed–loop ventilation mode for use in intensive care unit (ICU) patients, is equipped with algorithms that automatically adjust settings on the basis of physiologic signals and patient’s activity. Here we describe its effectiveness, safety, and efficacy in various types of ICU patients. Areas covered: A systematic search conducted in MEDLINE, EMBASE, the Cochrane Central register of Controlled Trials (CENTRAL), and in Google Scholar identified 10 randomized clinical trials. Expert opinion: Studies suggest INTELLiVENT–ASV to be an effective automated mode with regard to the titrations of tidal volume, airway pressure, and oxygen. INTELLiVENT–ASV is as safe as conventional modes. However, thus far studies have not shown INTELLiVENT–ASV to be superior to conventional modes with regard to duration of ventilation and other patient–centered outcomes. Future studies are needed to test its efficacy.

AB - Introduction: INTELLiVENT–Adaptive Support Ventilation (INTELLiVENT–ASV), an advanced closed–loop ventilation mode for use in intensive care unit (ICU) patients, is equipped with algorithms that automatically adjust settings on the basis of physiologic signals and patient’s activity. Here we describe its effectiveness, safety, and efficacy in various types of ICU patients. Areas covered: A systematic search conducted in MEDLINE, EMBASE, the Cochrane Central register of Controlled Trials (CENTRAL), and in Google Scholar identified 10 randomized clinical trials. Expert opinion: Studies suggest INTELLiVENT–ASV to be an effective automated mode with regard to the titrations of tidal volume, airway pressure, and oxygen. INTELLiVENT–ASV is as safe as conventional modes. However, thus far studies have not shown INTELLiVENT–ASV to be superior to conventional modes with regard to duration of ventilation and other patient–centered outcomes. Future studies are needed to test its efficacy.

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KW - automated ventilation

KW - closed–loop ventilation

KW - effectiveness

KW - efficacy

KW - INTELLiVENT–ASV

KW - intensive care unit

KW - invasive ventilation

KW - protective ventilation

KW - safety

KW - Intensive Care Units

KW - Humans

KW - Lung

KW - Tidal Volume

KW - Respiration, Artificial

KW - Critical Care

UR - https://www.scopus.com/pages/publications/85110541924

U2 - 10.1080/17476348.2021.1933450

DO - 10.1080/17476348.2021.1933450

M3 - Article

C2 - 34047244

AN - SCOPUS:85110541924

SN - 1747-6348

VL - 15

SP - 1403

EP - 1413

JO - Expert Review of Respiratory Medicine

JF - Expert Review of Respiratory Medicine

IS - 11

ER -

Effectiveness, safety and efficacy of INTELLiVENT–adaptive support ventilation, a closed–loop ventilation mode for use in ICU patients–a systematic review

Abstract

Bibliographical note

Funding

UN SDGs

Keywords

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