Dynamics of exchange in linear and cyclic supramolecular aggregates based on quadruple hydrogen bonding

R.P. Sijbesma; S.H.M. Sontjens; A.T. Cate, ten; P.Y.W. Dankers; E.W. Meijer

Dynamics of exchange in linear and cyclic supramolecular aggregates based on quadruple hydrogen bonding

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic

Abstract

Due to the high dimerization const. of ureidopyrimidinone (UPy), mols. contg. two such units form large polymeric aggregates, which are in equil. with cyclic species. We have investigated the dynamics of exchange in solns. of bifunctional compds. 1 and 2, using EXSY 2D-NMR and size exclusion chromatog. (SEC). Exchange spectroscopy on mixed linear aggregates of 1a and 1b shows that the kinetics of exchange between assocd. UPy units is different from that in monofunctional compds., and takes place via a long-lived intermediate. Simulation of size-exclusion chromatograms of compds. 2 show that exchange of mols. between cyclic dimers is fast on the chromatog. timescale, although it is slow on the NMR timescale. [on SciFinder (R)]

Original language	English
Title of host publication	Abstracts of Papers, 224th ACS National Meeting, Boston, MA, United States, August 18-22, 2002
Place of Publication	Washington
Publisher	American Chemical Society
Pages	ORGN-313
ISBN (Print)	0-8412-3840-5
Publication status	Published - 2002
Event	224th ACS National Meeting - Boston, United States Duration: 18 Aug 2002 → 22 Aug 2002

Conference

Conference	224th ACS National Meeting
Country/Territory	United States
City	Boston
Period	18/08/02 → 22/08/02

Cite this

@inproceedings{7e7814243615466dbd387d79493f6308,

title = "Dynamics of exchange in linear and cyclic supramolecular aggregates based on quadruple hydrogen bonding",

abstract = "Due to the high dimerization const. of ureidopyrimidinone (UPy), mols. contg. two such units form large polymeric aggregates, which are in equil. with cyclic species. We have investigated the dynamics of exchange in solns. of bifunctional compds. 1 and 2, using EXSY 2D-NMR and size exclusion chromatog. (SEC). Exchange spectroscopy on mixed linear aggregates of 1a and 1b shows that the kinetics of exchange between assocd. UPy units is different from that in monofunctional compds., and takes place via a long-lived intermediate. Simulation of size-exclusion chromatograms of compds. 2 show that exchange of mols. between cyclic dimers is fast on the chromatog. timescale, although it is slow on the NMR timescale. [on SciFinder (R)]",

author = "R.P. Sijbesma and S.H.M. Sontjens and \{Cate, ten\}, A.T. and P.Y.W. Dankers and E.W. Meijer",

year = "2002",

language = "English",

isbn = "0-8412-3840-5",

pages = "ORGN--313",

booktitle = "Abstracts of Papers, 224th ACS National Meeting, Boston, MA, United States, August 18-22, 2002",

publisher = "American Chemical Society",

address = "United States",

note = "224th ACS National Meeting ; Conference date: 18-08-2002 Through 22-08-2002",

}

Sijbesma, RP , Sontjens, SHM, Cate, ten, AT, Dankers, PYW & Meijer, EW 2002, Dynamics of exchange in linear and cyclic supramolecular aggregates based on quadruple hydrogen bonding. in Abstracts of Papers, 224th ACS National Meeting, Boston, MA, United States, August 18-22, 2002. American Chemical Society, Washington, pp. ORGN-313, 224th ACS National Meeting, Boston, Massachusetts, United States, 18/08/02.

Dynamics of exchange in linear and cyclic supramolecular aggregates based on quadruple hydrogen bonding. / Sijbesma, R.P.; Sontjens, S.H.M.; Cate, ten, A.T. et al.
Abstracts of Papers, 224th ACS National Meeting, Boston, MA, United States, August 18-22, 2002. Washington: American Chemical Society, 2002. p. ORGN-313.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic

TY - GEN

T1 - Dynamics of exchange in linear and cyclic supramolecular aggregates based on quadruple hydrogen bonding

AU - Sijbesma, R.P.

AU - Sontjens, S.H.M.

AU - Cate, ten, A.T.

AU - Dankers, P.Y.W.

AU - Meijer, E.W.

PY - 2002

Y1 - 2002

N2 - Due to the high dimerization const. of ureidopyrimidinone (UPy), mols. contg. two such units form large polymeric aggregates, which are in equil. with cyclic species. We have investigated the dynamics of exchange in solns. of bifunctional compds. 1 and 2, using EXSY 2D-NMR and size exclusion chromatog. (SEC). Exchange spectroscopy on mixed linear aggregates of 1a and 1b shows that the kinetics of exchange between assocd. UPy units is different from that in monofunctional compds., and takes place via a long-lived intermediate. Simulation of size-exclusion chromatograms of compds. 2 show that exchange of mols. between cyclic dimers is fast on the chromatog. timescale, although it is slow on the NMR timescale. [on SciFinder (R)]

AB - Due to the high dimerization const. of ureidopyrimidinone (UPy), mols. contg. two such units form large polymeric aggregates, which are in equil. with cyclic species. We have investigated the dynamics of exchange in solns. of bifunctional compds. 1 and 2, using EXSY 2D-NMR and size exclusion chromatog. (SEC). Exchange spectroscopy on mixed linear aggregates of 1a and 1b shows that the kinetics of exchange between assocd. UPy units is different from that in monofunctional compds., and takes place via a long-lived intermediate. Simulation of size-exclusion chromatograms of compds. 2 show that exchange of mols. between cyclic dimers is fast on the chromatog. timescale, although it is slow on the NMR timescale. [on SciFinder (R)]

M3 - Conference contribution

SN - 0-8412-3840-5

SP - ORGN-313

BT - Abstracts of Papers, 224th ACS National Meeting, Boston, MA, United States, August 18-22, 2002

PB - American Chemical Society

CY - Washington

T2 - 224th ACS National Meeting

Y2 - 18 August 2002 through 22 August 2002

ER -

Dynamics of exchange in linear and cyclic supramolecular aggregates based on quadruple hydrogen bonding

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Conference

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