Abstract
Upcoming generations of highly sensitive and miniaturized biosensing systems need target capture methods that are
as efficient and as rapid as possible. Magnetic particles can be used to efficiently capture targets from liquid. We show
that target capture can be accelerated by at least one order of magnitude by using time-dependent magnetic fields that
actuate ensembles of magnetic particles. Furthermore we exploit the repulsive magnetic dipole-dipole interaction
between particles near a surface, in order to undo magnetically-induced aggregation of particles and retrieve single
particles for further assaying. By combining the approaches, a novel assay concept is proposed in which dynamic
magnetic particle actuation is used across all assay steps.
| Original language | English |
|---|---|
| Title of host publication | 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2013) : Freiburg, Germany, 27 - 31 October 2013 |
| Place of Publication | Red Hook, NY |
| Publisher | Curran Associates |
| Pages | 209-211 |
| Volume | 1 |
| ISBN (Print) | 978-1-63266-624-6 |
| Publication status | Published - 2013 |
| Event | 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 - Freiburg, Germany Duration: 27 Oct 2013 → 31 Oct 2013 Conference number: 17 http://www.microtasconferences.org/microtas2013/ |
Conference
| Conference | 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 |
|---|---|
| Abbreviated title | MicroTAS |
| Country/Territory | Germany |
| City | Freiburg |
| Period | 27/10/13 → 31/10/13 |
| Internet address |