Dynamic kinetic resolution for the synthesis of esters, amides and acids using lipases

  • Kam Loon Fow
  • , Yongzhong Zhu
  • , Gaik Khuan Chuah
  • , Stephan Jaenicke
  • , S.F.G.M. van Nispen
  • , J. van Buijtenen
  • , J.A.J.M. Vekemans
  • , J. Meuldijk
  • , L.A. Hulshof
  • , Michael Page
  • , John Blacker
  • , Matthew Stirling
  • , Soo Byung Ko
  • , Mahn Joo Kim
  • , Jaiwook Park
  • , Stéphane Gastaldi
  • , Gérard Gil
  • , Michèle P. Bertrand
  • , A. H. Kamaruddin
  • , F. Hamzah
  • A. H. Kamaruddin, F. Hamzah, Matthew Truppo, David Pollard, Jeffrey Moore, Paul Devine

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Original languageEnglish
Title of host publicationPractical Methods for Biocatalysis and Biotransformations
EditorsJohn Whittall, Peter Sutton
Place of PublicationHoboken
PublisherWiley
Chapter4
Pages133-164
Number of pages32
ISBN (Electronic)9780470748589
ISBN (Print)9780470519271
DOIs
Publication statusPublished - 15 Dec 2009

Keywords

  • Bis(tetrafluorosuccinato)-bridged Ru(II) complex 1
  • Chemoenzymatic dynamic kinetic resolution of (S)-Ibuprofen
  • DKR method, applied to secondary alcohols
  • Dynamic kinetic resolution for ester, amide and acid synthesis using lipases
  • Dynamic kinetic resolution of 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline
  • Dynamic kinetic resolution of primary amines with recyclable palladium nanocatalyst (Pd/AlO(OH)) for racemization
  • One-pot dynamic kinetic resolution (DKR) of (-)-1-phenylethanol lipase esterification in presence of zeolite beta
  • Procedure 1 - synthesis of (R)-1-phenylethyl octanoate
  • Procedure 2 - hydrolysis of (R)-1-phenylethyl octanoate
  • Synthesis of (R)-butyrate esters of secondary alcohols by DKR

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