Dynamic kinetic resolution for the synthesis of esters, amides and acids using lipases

Kam Loon Fow, Yongzhong Zhu, Gaik Khuan Chuah, Stephan Jaenicke, S.F.G.M. van Nispen, J. van Buijtenen, J.A.J.M. Vekemans, J. Meuldijk, L.A. Hulshof, Michael Page, John Blacker, Matthew Stirling, Soo Byung Ko, Mahn Joo Kim, Jaiwook Park, Stéphane Gastaldi, Gérard Gil, Michèle P. Bertrand, A. H. Kamaruddin, F. HamzahA. H. Kamaruddin, F. Hamzah, Matthew Truppo, David Pollard, Jeffrey Moore, Paul Devine

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

Original languageEnglish
Title of host publicationPractical Methods for Biocatalysis and Biotransformations
EditorsJohn Whittall, Peter Sutton
Place of PublicationHoboken
PublisherWiley
Chapter4
Pages133-164
Number of pages32
ISBN (Electronic)9780470748589
ISBN (Print)9780470519271
DOIs
Publication statusPublished - 15 Dec 2009

Keywords

  • Bis(tetrafluorosuccinato)-bridged Ru(II) complex 1
  • Chemoenzymatic dynamic kinetic resolution of (S)-Ibuprofen
  • DKR method, applied to secondary alcohols
  • Dynamic kinetic resolution for ester, amide and acid synthesis using lipases
  • Dynamic kinetic resolution of 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline
  • Dynamic kinetic resolution of primary amines with recyclable palladium nanocatalyst (Pd/AlO(OH)) for racemization
  • One-pot dynamic kinetic resolution (DKR) of (-)-1-phenylethanol lipase esterification in presence of zeolite beta
  • Procedure 1 - synthesis of (R)-1-phenylethyl octanoate
  • Procedure 2 - hydrolysis of (R)-1-phenylethyl octanoate
  • Synthesis of (R)-butyrate esters of secondary alcohols by DKR

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