Does contrast ultrasound dispersion imaging reveal changes in tortuosity? : a comparison with acoustic angiography

A. Panfilova, M. Mischi, H. Wijkstra, R.J.G. van Sloun, L. Demi, S. Shelton, P. Dayton

Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

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Abstract

Higher microvascular density with tortuous and irregular vessels are hallmarks of cancer vasculature. These alterations can be captured by contrast ultrasound dispersion imaging (CUDI) and acoustic angiography (AA) at different scales: CUDI aims at obtaining an implicit measure of structural alteration by determining the dispersion kinetics of contrast agents. At a smaller scale, AA images the vascular architecture by detecting the high-frequency components generated with ultrasound contrast agents (UCA). This work shows the performance of these techniques by imaging cancerous and control regions in 3 rat xenograft models. Furthermore, it investigates the diagnostic value of the vascular features extracted using CUDI and AA with the aim to answer the question: does CUDI reveal changes in vascular tortuosity?
Original languageEnglish
Title of host publication2016 IEEE International Ultrasonics Symposium (IUS)
Place of PublicationPiscataway
PublisherInstitute of Electrical and Electronics Engineers
Pages1-4
Number of pages4
DOIs
Publication statusPublished - 2016
Event2016 IEEE International Ultrasonics Symposium (IUS 2016) - Convention Center Vinci, Tours, France
Duration: 18 Sep 201621 Sep 2016
http://sites.ieee.org/ius-2016/

Conference

Conference2016 IEEE International Ultrasonics Symposium (IUS 2016)
Abbreviated titleIUS 2016
CountryFrance
CityTours
Period18/09/1621/09/16
Internet address

Keywords

  • Cancer, Acoustic angiography,
  • Contrastenhanced

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