The yields of radicals trapped on DNA, measured by EPR spectroscopy of oligodeoxyribonucleotide crystals (the EPR spectrum of a single crystal of d(CCCTAGGG) is shown), are found to be very high (0.7 µmol¿J-1) and insensitive to long-range (>106 base pairs) versus short-range stacking (8 base pairs) of the bases. These observations are evidence that DNA at 4 K has the properties of an insulator and argue against DNA acting as a "molecular wire".
|Journal||Angewandte Chemie - International Edition|
|Publication status||Published - 1999|
Debije, M. G., Milano, M. T., & Bernhard, W. A. (1999). DNA responds to ionizing radiation as an insulator, not as a "molecular wire". Angewandte Chemie - International Edition, 38(18), 2752-2756. https://doi.org/10.1002/(SICI)1521-3773(19990917)38:18<2752::AID-ANIE2752>3.0.CO;2-U, https://doi.org/10.1002/(SICI)1521-3773(19990917)38:18<2752::AID-ANIE2752>3.3.CO;2-L