TY - JOUR
T1 - DNA responds to ionizing radiation as an insulator, not as a "molecular wire"
AU - Debije, M.G.
AU - Milano, M.T.
AU - Bernhard, W.A.
PY - 1999
Y1 - 1999
N2 - The yields of radicals trapped on DNA, measured by EPR spectroscopy of oligodeoxyribonucleotide crystals (the EPR spectrum of a single crystal of d(CCCTAGGG) is shown), are found to be very high (0.7 µmol¿J-1) and insensitive to long-range (>106 base pairs) versus short-range stacking (8 base pairs) of the bases. These observations are evidence that DNA at 4 K has the properties of an insulator and argue against DNA acting as a "molecular wire".
AB - The yields of radicals trapped on DNA, measured by EPR spectroscopy of oligodeoxyribonucleotide crystals (the EPR spectrum of a single crystal of d(CCCTAGGG) is shown), are found to be very high (0.7 µmol¿J-1) and insensitive to long-range (>106 base pairs) versus short-range stacking (8 base pairs) of the bases. These observations are evidence that DNA at 4 K has the properties of an insulator and argue against DNA acting as a "molecular wire".
U2 - 10.1002/(SICI)1521-3773(19990917)38:18<2752::AID-ANIE2752>3.0.CO;2-U
DO - 10.1002/(SICI)1521-3773(19990917)38:18<2752::AID-ANIE2752>3.0.CO;2-U
M3 - Article
SN - 0570-0833
VL - 38
SP - 2752
EP - 2756
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
IS - 18
ER -