TY - JOUR
T1 - DNA-functionalized supramolecular polymers
T2 - dynamic multicomponent assemblies with emergent properties
AU - Wijnands, Sjors P.W.
AU - Meijer, E.W.
AU - Merkx, Maarten
PY - 2019/7/17
Y1 - 2019/7/17
N2 - Recent years have witnessed an increasing interest in hybrid molecular systems in which the programmability of DNA hybridization is used to introduce enhanced molecular control in synthetic systems. The first examples of DNA-functionalized supramolecular polymers have been reported only recently, but have already revealed structural and functional properties that are not easily obtained in either synthetic supramolecular polymers or DNA-only based systems. In this Topical Review, we provide an overview of the various forms of additional control offered by DNA hybridization for different types of supramolecular polymers and discuss how orthogonal supramolecular interactions in these hybrid systems can give rise to emergent structural and functional properties.
AB - Recent years have witnessed an increasing interest in hybrid molecular systems in which the programmability of DNA hybridization is used to introduce enhanced molecular control in synthetic systems. The first examples of DNA-functionalized supramolecular polymers have been reported only recently, but have already revealed structural and functional properties that are not easily obtained in either synthetic supramolecular polymers or DNA-only based systems. In this Topical Review, we provide an overview of the various forms of additional control offered by DNA hybridization for different types of supramolecular polymers and discuss how orthogonal supramolecular interactions in these hybrid systems can give rise to emergent structural and functional properties.
UR - http://www.scopus.com/inward/record.url?scp=85063375314&partnerID=8YFLogxK
U2 - 10.1021/acs.bioconjchem.9b00095
DO - 10.1021/acs.bioconjchem.9b00095
M3 - Review article
C2 - 30860819
AN - SCOPUS:85063375314
SN - 1043-1802
VL - 30
SP - 1905
EP - 1914
JO - Bioconjugate Chemistry
JF - Bioconjugate Chemistry
IS - 7
ER -