TY - JOUR
T1 - Dimerization of papain induced by mercuric chloride and a bifunctional organic mercurial
AU - Sluyterman, L.A.A.E.
AU - Wijdenes, J.
AU - Voorn, G.
PY - 1977
Y1 - 1977
N2 - The bifunctional mercurial meso-1,4-bis(acetatomercuri)-2,3-diethoxybutane and mercuric chloride are capable of dimerizing papain, by the attachment of the thiol group of two molecules of papain to each molecule of reagent. This is evident from the titration data, gel filtration and sedimentation equilibrium. The conformational change of papain necessary for this reaction is discussed.
AB - The bifunctional mercurial meso-1,4-bis(acetatomercuri)-2,3-diethoxybutane and mercuric chloride are capable of dimerizing papain, by the attachment of the thiol group of two molecules of papain to each molecule of reagent. This is evident from the titration data, gel filtration and sedimentation equilibrium. The conformational change of papain necessary for this reaction is discussed.
U2 - 10.1111/j.1432-1033.1977.tb11647.x
DO - 10.1111/j.1432-1033.1977.tb11647.x
M3 - Article
SN - 0014-2956
VL - 77
SP - 107
EP - 111
JO - European Journal of Biochemistry
JF - European Journal of Biochemistry
IS - 1
ER -