Developing from child to adult:risk factors for poor psychosocial outcome in adolescents and young adults with epilepsy.

R.P Geerlings, Albert Aldenkamp, Laura Gottmer-Welschen, Peter de With, Sveta Zinger, A.L. Staa, Anton de Louw

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Abstract

Introduction
Childhood-onset epilepsy during the years of transition to adulthood may affect normal social, physical, and mental development, frequently leading to psychosocial and health-related problems in the long term.
Objective
This study aimed to describe the main characteristics of patients in transition and to identify risk factors for poor psychosocial outcome in adolescents and young adults with epilepsy.
Methods
Patients with epilepsy, 15–25 years of age, who visited the Kempenhaeghe Epilepsy Transition Clinic from March 2012 to December 2014 were included (n = 138). Predefined risk scores for medical, educational/occupational status, and independence/separation/identity were obtained, along with individual risk profile scores for poor psychosocial outcome. Multivariate linear regression analysis and discriminant analysis were used to identify variables associated with an increased risk of poor long-term psychosocial outcome.
Results
Demographic, epilepsy-related, and psychosocial variables associated with a high risk of poor long-term outcome were lower intelligence, higher seizure frequency, ongoing seizures, and an unsupportive and unstable family environment. Using the aforementioned factors in combination, we were able to correctly classify the majority (55.1%) of the patients regarding their risk of poor psychosocial outcome.
Conclusion
Our analysis may allow early identification of patients at high risk of prevention, preferably at pretransition age. The combination of a chronic refractory epilepsy and an unstable family environment constitutes a higher risk of transition problems and poor outcome in adulthood. As a consequence, early interventions should be put into place to protect youth at risk of poor transition outcome.
Original languageEnglish
Pages (from-to)182-190
JournalEpilepsy and Behavior
Volume51
DOIs
Publication statusPublished - Oct 2015

Keywords

  • Transition to adult care
  • Risk factors for transition
  • Epilepsy
  • Transition clinic

Cite this

@article{60e5e2429b354da8ad6105b1e90b93b3,
title = "Developing from child to adult:risk factors for poor psychosocial outcome in adolescents and young adults with epilepsy.",
abstract = "IntroductionChildhood-onset epilepsy during the years of transition to adulthood may affect normal social, physical, and mental development, frequently leading to psychosocial and health-related problems in the long term.ObjectiveThis study aimed to describe the main characteristics of patients in transition and to identify risk factors for poor psychosocial outcome in adolescents and young adults with epilepsy.MethodsPatients with epilepsy, 15–25 years of age, who visited the Kempenhaeghe Epilepsy Transition Clinic from March 2012 to December 2014 were included (n = 138). Predefined risk scores for medical, educational/occupational status, and independence/separation/identity were obtained, along with individual risk profile scores for poor psychosocial outcome. Multivariate linear regression analysis and discriminant analysis were used to identify variables associated with an increased risk of poor long-term psychosocial outcome.ResultsDemographic, epilepsy-related, and psychosocial variables associated with a high risk of poor long-term outcome were lower intelligence, higher seizure frequency, ongoing seizures, and an unsupportive and unstable family environment. Using the aforementioned factors in combination, we were able to correctly classify the majority (55.1{\%}) of the patients regarding their risk of poor psychosocial outcome.ConclusionOur analysis may allow early identification of patients at high risk of prevention, preferably at pretransition age. The combination of a chronic refractory epilepsy and an unstable family environment constitutes a higher risk of transition problems and poor outcome in adulthood. As a consequence, early interventions should be put into place to protect youth at risk of poor transition outcome.",
keywords = "Transition to adult care, Risk factors for transition, Epilepsy, Transition clinic",
author = "R.P Geerlings and Albert Aldenkamp and Laura Gottmer-Welschen and {de With}, Peter and Sveta Zinger and A.L. Staa and {de Louw}, Anton",
year = "2015",
month = "10",
doi = "10.1016/j.yebeh.2015.07.035",
language = "English",
volume = "51",
pages = "182--190",
journal = "Epilepsy and Behavior",
issn = "1525-5050",
publisher = "Academic Press Inc.",

}

Developing from child to adult:risk factors for poor psychosocial outcome in adolescents and young adults with epilepsy. / Geerlings, R.P; Aldenkamp, Albert; Gottmer-Welschen, Laura; de With, Peter; Zinger, Sveta; Staa, A.L.; de Louw, Anton.

In: Epilepsy and Behavior, Vol. 51, 10.2015, p. 182-190.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Developing from child to adult:risk factors for poor psychosocial outcome in adolescents and young adults with epilepsy.

AU - Geerlings, R.P

AU - Aldenkamp, Albert

AU - Gottmer-Welschen, Laura

AU - de With, Peter

AU - Zinger, Sveta

AU - Staa, A.L.

AU - de Louw, Anton

PY - 2015/10

Y1 - 2015/10

N2 - IntroductionChildhood-onset epilepsy during the years of transition to adulthood may affect normal social, physical, and mental development, frequently leading to psychosocial and health-related problems in the long term.ObjectiveThis study aimed to describe the main characteristics of patients in transition and to identify risk factors for poor psychosocial outcome in adolescents and young adults with epilepsy.MethodsPatients with epilepsy, 15–25 years of age, who visited the Kempenhaeghe Epilepsy Transition Clinic from March 2012 to December 2014 were included (n = 138). Predefined risk scores for medical, educational/occupational status, and independence/separation/identity were obtained, along with individual risk profile scores for poor psychosocial outcome. Multivariate linear regression analysis and discriminant analysis were used to identify variables associated with an increased risk of poor long-term psychosocial outcome.ResultsDemographic, epilepsy-related, and psychosocial variables associated with a high risk of poor long-term outcome were lower intelligence, higher seizure frequency, ongoing seizures, and an unsupportive and unstable family environment. Using the aforementioned factors in combination, we were able to correctly classify the majority (55.1%) of the patients regarding their risk of poor psychosocial outcome.ConclusionOur analysis may allow early identification of patients at high risk of prevention, preferably at pretransition age. The combination of a chronic refractory epilepsy and an unstable family environment constitutes a higher risk of transition problems and poor outcome in adulthood. As a consequence, early interventions should be put into place to protect youth at risk of poor transition outcome.

AB - IntroductionChildhood-onset epilepsy during the years of transition to adulthood may affect normal social, physical, and mental development, frequently leading to psychosocial and health-related problems in the long term.ObjectiveThis study aimed to describe the main characteristics of patients in transition and to identify risk factors for poor psychosocial outcome in adolescents and young adults with epilepsy.MethodsPatients with epilepsy, 15–25 years of age, who visited the Kempenhaeghe Epilepsy Transition Clinic from March 2012 to December 2014 were included (n = 138). Predefined risk scores for medical, educational/occupational status, and independence/separation/identity were obtained, along with individual risk profile scores for poor psychosocial outcome. Multivariate linear regression analysis and discriminant analysis were used to identify variables associated with an increased risk of poor long-term psychosocial outcome.ResultsDemographic, epilepsy-related, and psychosocial variables associated with a high risk of poor long-term outcome were lower intelligence, higher seizure frequency, ongoing seizures, and an unsupportive and unstable family environment. Using the aforementioned factors in combination, we were able to correctly classify the majority (55.1%) of the patients regarding their risk of poor psychosocial outcome.ConclusionOur analysis may allow early identification of patients at high risk of prevention, preferably at pretransition age. The combination of a chronic refractory epilepsy and an unstable family environment constitutes a higher risk of transition problems and poor outcome in adulthood. As a consequence, early interventions should be put into place to protect youth at risk of poor transition outcome.

KW - Transition to adult care

KW - Risk factors for transition

KW - Epilepsy

KW - Transition clinic

U2 - 10.1016/j.yebeh.2015.07.035

DO - 10.1016/j.yebeh.2015.07.035

M3 - Article

C2 - 26291772

VL - 51

SP - 182

EP - 190

JO - Epilepsy and Behavior

JF - Epilepsy and Behavior

SN - 1525-5050

ER -