Determination of physiological parameters of tissue from dynamic contrast-enhanced MR data

M. Breeuwer (Inventor), M. Mischi (Inventor), H. Wijkstra (Inventor)

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Abstract

A method of determining microvascular architecture is disclosed. Dynamic contrast-enhanced magnetic resonance data acquired from a contrast agent administered to at least a part of a subject to be examined. From the dynamic contrast-enhanced magnetic resonance data a leakage parameter (k ep) and a dispersion parameter (k) are computed. Effects of both convective dispersion and extravasation kinetics of contrast agent are taken into account.
Original languageEnglish
Patent numberWO2014162246 A1
Priority date3/04/13
Publication statusPublished - 9 Oct 2014

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magnetic resonance
leakage
kinetics

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abstract = "A method of determining microvascular architecture is disclosed. Dynamic contrast-enhanced magnetic resonance data acquired from a contrast agent administered to at least a part of a subject to be examined. From the dynamic contrast-enhanced magnetic resonance data a leakage parameter (k ep) and a dispersion parameter (k) are computed. Effects of both convective dispersion and extravasation kinetics of contrast agent are taken into account.",
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AB - A method of determining microvascular architecture is disclosed. Dynamic contrast-enhanced magnetic resonance data acquired from a contrast agent administered to at least a part of a subject to be examined. From the dynamic contrast-enhanced magnetic resonance data a leakage parameter (k ep) and a dispersion parameter (k) are computed. Effects of both convective dispersion and extravasation kinetics of contrast agent are taken into account.

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