Detection of glucose and triglycerides using information visualization methods to process impedance spectroscopy data

Marli L. Moraes; Laís Petri; Victor Oliveira; Clarissa A. Olivati; Maria Cristina F. De Oliveira; Fernando V. Paulovich; Osvaldo N. Oliveira; Marystela Ferreira

doi:10.1016/j.snb.2012.02.046

Detection of glucose and triglycerides using information visualization methods to process impedance spectroscopy data

Marli L. Moraes, Laís Petri, Victor Oliveira, Clarissa A. Olivati, Maria Cristina F. De Oliveira, Fernando V. Paulovich, Osvaldo N. Oliveira, Marystela Ferreira

Research output: Contribution to journal › Article › Academic › peer-review

20 Citations (Scopus)

Abstract

In this paper we discuss the detection of glucose and triglycerides using information visualization methods to process impedance spectroscopy data. The sensing units contained either lipase or glucose oxidase immobilized in layer-by-layer (LbL) films deposited onto interdigitated electrodes. The optimization consisted in identifying which part of the electrical response and combination of sensing units yielded the best distinguishing ability. It is shown that complete separation can be obtained for a range of concentrations of glucose and triglyceride when the interactive document map (IDMAP) technique is used to project the data into a two-dimensional plot. Most importantly, the optimization procedure can be extended to other types of biosensors, thus increasing the versatility of analysis provided by tailored molecular architectures exploited with various detection principles.

Original language	English
Pages (from-to)	231-238
Number of pages	8
Journal	Sensors and Actuators, B: Chemical
Volume	166-167
DOIs	https://doi.org/10.1016/j.snb.2012.02.046
Publication status	Published - 20 May 2012

Bibliographical note

Funding Information:
This work was supported by FAPESP , CNPq , Capes and rede nBioNet . We also thank LNLS (Brazil) for providing interdigitated electrodes (project LMF 11325).

Funding

This work was supported by FAPESP , CNPq , Capes and rede nBioNet . We also thank LNLS (Brazil) for providing interdigitated electrodes (project LMF 11325).

Keywords

Biosensor
Glucose oxidase
Information visualization
Lipase
Multidimensional projection
Nanostructured film

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10.1016/j.snb.2012.02.046

Cite this

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title = "Detection of glucose and triglycerides using information visualization methods to process impedance spectroscopy data",

abstract = "In this paper we discuss the detection of glucose and triglycerides using information visualization methods to process impedance spectroscopy data. The sensing units contained either lipase or glucose oxidase immobilized in layer-by-layer (LbL) films deposited onto interdigitated electrodes. The optimization consisted in identifying which part of the electrical response and combination of sensing units yielded the best distinguishing ability. It is shown that complete separation can be obtained for a range of concentrations of glucose and triglyceride when the interactive document map (IDMAP) technique is used to project the data into a two-dimensional plot. Most importantly, the optimization procedure can be extended to other types of biosensors, thus increasing the versatility of analysis provided by tailored molecular architectures exploited with various detection principles.",

keywords = "Biosensor, Glucose oxidase, Information visualization, Lipase, Multidimensional projection, Nanostructured film",

author = "Moraes, {Marli L.} and La{\'i}s Petri and Victor Oliveira and Olivati, {Clarissa A.} and {De Oliveira}, {Maria Cristina F.} and Paulovich, {Fernando V.} and Oliveira, {Osvaldo N.} and Marystela Ferreira",

note = "Funding Information: This work was supported by FAPESP , CNPq , Capes and rede nBioNet . We also thank LNLS (Brazil) for providing interdigitated electrodes (project LMF 11325). ",

year = "2012",

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doi = "10.1016/j.snb.2012.02.046",

language = "English",

volume = "166-167",

pages = "231--238",

journal = "Sensors and Actuators, B: Chemical",

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T1 - Detection of glucose and triglycerides using information visualization methods to process impedance spectroscopy data

AU - Moraes, Marli L.

AU - Petri, Laís

AU - Oliveira, Victor

AU - Olivati, Clarissa A.

AU - De Oliveira, Maria Cristina F.

AU - Paulovich, Fernando V.

AU - Oliveira, Osvaldo N.

AU - Ferreira, Marystela

N1 - Funding Information: This work was supported by FAPESP , CNPq , Capes and rede nBioNet . We also thank LNLS (Brazil) for providing interdigitated electrodes (project LMF 11325).

PY - 2012/5/20

Y1 - 2012/5/20

N2 - In this paper we discuss the detection of glucose and triglycerides using information visualization methods to process impedance spectroscopy data. The sensing units contained either lipase or glucose oxidase immobilized in layer-by-layer (LbL) films deposited onto interdigitated electrodes. The optimization consisted in identifying which part of the electrical response and combination of sensing units yielded the best distinguishing ability. It is shown that complete separation can be obtained for a range of concentrations of glucose and triglyceride when the interactive document map (IDMAP) technique is used to project the data into a two-dimensional plot. Most importantly, the optimization procedure can be extended to other types of biosensors, thus increasing the versatility of analysis provided by tailored molecular architectures exploited with various detection principles.

AB - In this paper we discuss the detection of glucose and triglycerides using information visualization methods to process impedance spectroscopy data. The sensing units contained either lipase or glucose oxidase immobilized in layer-by-layer (LbL) films deposited onto interdigitated electrodes. The optimization consisted in identifying which part of the electrical response and combination of sensing units yielded the best distinguishing ability. It is shown that complete separation can be obtained for a range of concentrations of glucose and triglyceride when the interactive document map (IDMAP) technique is used to project the data into a two-dimensional plot. Most importantly, the optimization procedure can be extended to other types of biosensors, thus increasing the versatility of analysis provided by tailored molecular architectures exploited with various detection principles.

KW - Biosensor

KW - Glucose oxidase

KW - Information visualization

KW - Lipase

KW - Multidimensional projection

KW - Nanostructured film

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M3 - Article

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SN - 0925-4005

VL - 166-167

SP - 231

EP - 238

JO - Sensors and Actuators, B: Chemical

JF - Sensors and Actuators, B: Chemical

ER -

Detection of glucose and triglycerides using information visualization methods to process impedance spectroscopy data

Abstract

Bibliographical note

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Keywords

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