Design and application of a modular and scalable electrochemical flow microreactor

Gabriele Laudadio, Wouter de Smet, Lisa Struik, Yiran Cao, Timothy Noël

Research output: Contribution to journalArticleAcademicpeer-review

67 Citations (Scopus)
2 Downloads (Pure)


Electrochemistry constitutes a mild, green and versatile activation method of organic molecules. Despite these innate advantages, its widespread use in organic chemistry has been hampered due to technical limitations, such as mass and heat transfer limitations which restraints the scalability of electrochemical methods. Herein, we describe an undivided-cell electrochemical flow reactor with a flexible reactor volume. This enables its use in two different modes, which are highly relevant for flow chemistry applications, including a serial (volume ranging from 88 μL/channel up to 704 μL) or a parallel mode (numbering-up). The electrochemical flow reactor was subsequently assessed in two synthetic transformations, which confirms its versatility and scale-up potential.

Original languageEnglish
Pages (from-to)157-165
Number of pages9
JournalJournal of Flow Chemistry
Issue number3-4
Publication statusPublished - 1 Dec 2018


  • Electrochemistry
  • Flow chemistry
  • Reactor
  • Scalability


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