Demand controlled filtration, a high potential energy savings measure for cleanrooms?

In cleanrooms, high ventilation rates are being used. This is in line with the available guidelines. Normally the required air flows are applied 24/7 so the environmental cleanliness is not compromised. This therefore is an energy-intensive activity. As production is of higher economic importance than energy savings, cleanroom operators have put product safety and product yields first, giving energy efficiency a lower priority. The study described in this article
challenges the applied air change rates and more specifically the need for applying these rates 24/7. The research is based on real-life (in-situ) examples of pharmaceutical cleanrooms.