Degree of chemical functionalization of carbon nanotubes determine tissue distribution and excretion profile

K. T. Al-Jamal, A. Nunes, L. Methven, H. Ali-Boucetta, Li Shouping, F. Toma, M.A. Herrero, W.T. Al-Jamal, H.M.M. Eikelder, ten, J. Foster, S. Mather, M. Prato, M. Bianco, K. Kostarelos

Research output: Contribution to journalArticleAcademicpeer-review

109 Citations (Scopus)

Abstract

Getting rid of the tubes: An assessment of the retention of functionalized multi-walled carbon nanotubes (MWNTs) in the organs of mice was carried out using single photon emission computed tomography and quantitative scintigraphy (see scheme). Increasing the degree of functionalization on MWNTs enhanced renal clearance, while lower functionalization promoted reticuloendethelial system accumulation.
Original languageEnglish
Pages (from-to)6389-6393
Number of pages5
JournalAngewandte Chemie - International Edition
Volume51
Issue number26
DOIs
Publication statusPublished - 2012

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