Coupling of a pulse wave propagation model to a lumped parameter regulation model based on physiological mechanisms

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Abstract

We present a combination of a pulse wave propagation model with an extensive lumped parameter cerebral regulation model. Multiple physiological mechanisms contributing to autoregulation and neurovascular coupling lead to variable impedances in a finite 0-D element that is coupled to the cerebral outlets of 1-D wave propagation network. A simulation of global hemodynamics responding to clamping of an upstream vessel is demonstrated.
Original languageEnglish
Title of host publication3rd International Conference on Computational and Mathematical Biomedical Engineering,
EditorsP. Nithiarasu, R. Löhner, K.M. Liew
PublisherCMBE
Pages268-271
ISBN (Print)978-0-9562914-2-4
Publication statusPublished - 2013
Event3rd International Conference on Computational & Mathematical Biomedical Engineering (CMBE13) - City University of Hong Kong, Hong Kong, China
Duration: 16 Dec 201318 Dec 2013
http://www.compbiomed.net/2013/

Conference

Conference3rd International Conference on Computational & Mathematical Biomedical Engineering (CMBE13)
Abbreviated titleCMBE13
Country/TerritoryChina
CityHong Kong
Period16/12/1318/12/13
Internet address

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